精神病夫妇——共享药物还是错觉?

Julien Springs
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摘要

甲氧麻黄酮和亚甲基二氧基戊烷酮(MDPV)是在“浴盐”中发现的常见化合物。“浴盐”是一种娱乐性药物,它的受欢迎程度急剧上升,导致全国每年的急诊室就诊人数增加。由于服用者多为年轻人,且无精神病史,因此往往难以辨别症状是物质诱发的还是与器质性紊乱有关。我们的病人是一名38岁的女性,没有精神病史,她在两次通过过量服用和自残自杀未遂后来到急诊室。初步检查时,患者嗜睡,但可唤醒和定向。她赞同听觉和视觉幻觉,以及关于被儿子监视的偏执妄想。经进一步询问,患者入院前一天承认使用浴盐,尿液毒理学苯环素阳性。她入院以稳定病情,但尽管她的幻觉有所改善,她的妄想症仍然存在。她的丈夫也曾探望过她,他也表现出类似的偏执妄想,这让人怀疑她的症状是否真的是药物引起的,还是她与配偶共同患有精神病。出院前,她的幻觉和偏执在停止使用浴盐和开始使用奥氮平后得到改善。她能够获得一些洞察力,认识到这些错觉是假的,而她的丈夫仍然继续相信它们是真的。因此,我们得出结论,这对夫妇的精神病症状更可能与共同的浴盐有关,而不是共同的妄想。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Psychotic Couple--Sharing Drugs or Delusions?

Mephedrone and methylenedioxypyrovalerone (MDPV) are common compounds found in "Bath Salts," a recreational drug which has skyrocketed in popularity, resulting in increasing annual emergency room visits across the country. As users are often young and without previous psychiatric history it is often difficult to discern if symptoms are substance induced or related to an organic disorder. Our patient was a 38-year-old woman with no history of psychosis who presented to the emergency room following two failed suicide attempts via overdose and self-mutilation. On initial examination, the patient was somnolent yet arousable and oriented. She endorsed auditory and visual hallucinations as well as paranoid delusions regarding being spied on by her son. Upon further questioning, patient admitted to use of bath salts one day prior to admission and urine toxicology was positive for phenycyclidine. She was admitted for stabilization but despite improvement in her hallucinations, her paranoia persisted. She was visited by her husband who also expressed similar paranoid delusions, raising the question as to whether her symptoms were truly substance induced or if the patient was experiencing a shared psychotic disorder with her spouse. Prior to discharge, her hallucinations and paranoia had improved with abstinence from bath salts and the initiation of olanzapine. She was able to gain some insight, recognizing the delusions were false yet her husband still continued to believe they were true. As such, we concluded that the couple's psychotic symptoms were more likely related to shared bath salts rather than shared delusions.

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