Grete Kellenberger-Gujer:分子生物学研究先驱。

Bacteriophage Pub Date : 2016-04-05 eCollection Date: 2016-04-01 DOI:10.1080/21597081.2016.1173168
Sandra Citi, Douglas E Berg
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引用次数: 1

摘要

Grete Kellenberger-Gujer是瑞士分子生物学家,20世纪中期在日内瓦大学开创了噬菌体的基础研究。本文回顾了她的生活和职业故事,重点介绍了她对噬菌体生物学早期理解的基本贡献,通过她对一些现象的深刻分析,如温和噬菌体的溶原状态(λ)、基因重组、辐射的体内后果和DNA限制性修饰;论她的创作个性和与同龄人的互动以及她的学术进步如何受到当时性别、社会条件和文化态度的影响。她的故事在科学上很重要,从分子生物学时代开始的早期开始,就把科学界的特征透视出来,从社会学上也很重要,说明了无数的“玻璃天花板”,特别是在那个时候,经常阻碍有创造力的女性的进步。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Grete Kellenberger-Gujer: Molecular biology research pioneer.

Grete Kellenberger-Gujer was a Swiss molecular biologist who pioneered fundamental studies of bacteriophage in the mid-20(th) century at the University of Geneva. Her life and career stories are reviewed here, focusing on her fundamental contributions to our early understanding of phage biology via her insightful analyses of phenomena such as the lysogenic state of a temperate phage (λ), genetic recombination, radiation's in vivo consequences, and DNA restriction-modification; on her creative personality and interactions with peers; and how her academic advancement was affected by gender, societal conditions and cultural attitudes of the time. Her story is important scientifically, putting into perspective features of the scientific community from just before the molecular biology era started through its early years, and also sociologically, in illustrating the numerous "glass ceilings" that, especially then, often hampered the advancement of creative women.

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