从miRWalk2.0获取miRNA-Target相互作用信息

Q1 Biochemistry, Genetics and Molecular Biology

Current protocols in bioinformatics Pub Date : 2018-04-20 DOI:10.1002/cpbi.14

Alisha Parveen, Norbert Gretz, Harsh Dweep

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引用次数: 10

摘要

miRWalk2.0 (http://zmf.umm.uni-heidelberg.de/mirwalk2)是一个免费访问，定期更新的综合档案，提供最大的预测和实验验证的mirna -靶标相互作用的可用集合，具有各种新颖和独特的功能，以协助科学界。在miRWalk2.0中记录了11,748个mirna, 308,700个基因和68,460个lncrna之间约9.49亿次相互作用，其中包含5,146,217种不同类型的标识符，为收集丰富的信息提供了一站式站点。本文描述了如何从miRWalk2.0中获得miRNA-target相互作用的示意图工作流程。©2016 by John Wiley &儿子,Inc。

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Obtaining miRNA-Target Interaction Information from miRWalk2.0

miRWalk2.0 (http://zmf.umm.uni-heidelberg.de/mirwalk2) is a freely accessible, regularly updated comprehensive archive supplying the largest available collection of predicted and experimentally verified miRNA-target interactions, with various novel and unique features to assist the scientific community. Approximately 949 million interactions between 11,748 miRNAs, 308,700 genes, and 68,460 lncRNAs are documented in miRWalk2.0 with 5,146,217 different kinds of identifiers to offer a one-stop site to collect an abundance of information. This article describes a schematic workflow on how to obtain miRNA-target interactions from miRWalk2.0. © 2016 by John Wiley & Sons, Inc.

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Current protocols in bioinformatics Biochemistry, Genetics and Molecular Biology-Biochemistry

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期刊介绍： With Current Protocols in Bioinformatics, it"s easier than ever for the life scientist to become "fluent" in bioinformatics and master the exciting new frontiers opened up by DNA sequencing. Updated every three months in all formats, CPBI is constantly evolving to keep pace with the very latest discoveries and developments.