古吉拉特无症状年轻人代谢综合征的患病率和预测因素

International Journal of Chronic Diseases Pub Date : 2015-01-01 Epub Date: 2015-07-30 DOI:10.1155/2015/365217
Sharad R Jain, Komal H Shah, Himanshu N Acharya, Kaushik Barot, Kamal H Sharma
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引用次数: 0

摘要

背景。代谢综合征是导致动脉粥样硬化性心血管疾病的一组风险因素。我们的目的是评估代谢综合征(MS)在表面健康的古吉拉特年轻人中的发病率及其预测因素。研究方法这项基于人群的横断面研究共涉及 1500 名 20-40 岁的健康成年人。研究人员测量了人口统计学细节和临床数据,如体重指数 (BMI)、腰围 (WC) 和血压,并估算了脂蛋白 (a)、总胆固醇 (TC)、甘油三酯 (TG)、总血脂、低密度脂蛋白/高密度脂蛋白比率、TC/高密度脂蛋白比率和空腹血糖 (FBS)。结果。古吉拉特年轻人群(20-40 岁)中多发性硬化症的患病率为 16.0%(男性:21.5%;女性:10.8%),随着年龄的增长,代谢异常也随之增加,年轻人群(20-30 岁)中有 9.56% 的人患有多发性硬化症,而老年人群(31-40 岁)中有 24.57% 的人患有多发性硬化症。比值比分析表明,体重指数(1.120;95% CI:1.077-1.163;P <0.0001)是多发性硬化症的最强风险因素,紧随其后的是年龄的增长(1.100;95% CI:1.061-1.139;P <0.0001)。结论古吉拉特年轻人群中代谢综合征的流行加强了对该族群进行早期生活方式干预和宣传计划的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence and Predictors of Metabolic Syndrome in Young Asymptomatic Gujarati Population.

Background. Metabolic syndrome is a cluster of risk factors leading to the development of atherosclerotic cardiovascular diseases. We aimed to evaluate the prevalence of metabolic syndrome (MS) and its predictors in young and apparently healthy Gujarati individuals. Methods. This population based cross-sectional study involved a total of 1500 healthy adults of 20-40 years of age. Demographic details and clinical data such as body mass index (BMI), waist circumference (WC), and blood pressure were measured along with the estimations of lipoprotein (a), total cholesterol (TC), triglyceride (TG), total lipid, LDL/HDL ratio, TC/HDL ratio, and fasting blood glucose (FBS). Results. Overall in young Gujarati population (20-40 years) prevalence rates of MS were 16.0% (male: 21.5%; female: 10.8%) where the metabolic abnormalities increased with advanced age as 9.56% of the young population (20-30 years) had MS, in contrast to the 24.57% in the old (31-40 years). Odds ratio analysis had indicated BMI (1.120; 95% CI: 1.077-1.163; P < 0.0001) as the strongest risk factor for MS closely followed by advancing age (1.100; 95% CI: 1.061-1.139; P < 0.0001) levels. Conclusion. Prevalence of metabolic syndrome in young Gujarati population reinforces the need for early life style intervention and awareness programs in this ethnic group.

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