{"title":"[从化学药剂学到药理学的Magendie公式汇编(1821-1840)]。","authors":"Alain Ségal, Francis Trépardoux","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>With nine consecutive issues published from 1821 to 1836, the Formulaire concepted by Magendie as a usual tool for the medical precriptions, was first dedicated to the new chemical pharmaceuticals, mainly the pure alcaloids, strychnine, quinine and morphine, extracted from raw products. As well he included mineral chemicals, hydrocyanates, iodine and bromide, all supported by newly achieved works, from Pelletier, Caventou and others. Magendie perfectly skilled in animal experimentation, developped and standardized the as far as to evaluate the activity and safety degrees of these new components. It clearly anticipated the evaluation plan determined by the law for the registration of the new drugs in the twentieth century.</p>","PeriodicalId":13089,"journal":{"name":"Histoire des sciences medicales","volume":"49 2","pages":"141-56"},"PeriodicalIF":0.0000,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The Formulaires of Magendie (1821-1840) of the chemical pharmacy to pharmacology].\",\"authors\":\"Alain Ségal, Francis Trépardoux\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>With nine consecutive issues published from 1821 to 1836, the Formulaire concepted by Magendie as a usual tool for the medical precriptions, was first dedicated to the new chemical pharmaceuticals, mainly the pure alcaloids, strychnine, quinine and morphine, extracted from raw products. As well he included mineral chemicals, hydrocyanates, iodine and bromide, all supported by newly achieved works, from Pelletier, Caventou and others. Magendie perfectly skilled in animal experimentation, developped and standardized the as far as to evaluate the activity and safety degrees of these new components. It clearly anticipated the evaluation plan determined by the law for the registration of the new drugs in the twentieth century.</p>\",\"PeriodicalId\":13089,\"journal\":{\"name\":\"Histoire des sciences medicales\",\"volume\":\"49 2\",\"pages\":\"141-56\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Histoire des sciences medicales\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Histoire des sciences medicales","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[The Formulaires of Magendie (1821-1840) of the chemical pharmacy to pharmacology].
With nine consecutive issues published from 1821 to 1836, the Formulaire concepted by Magendie as a usual tool for the medical precriptions, was first dedicated to the new chemical pharmaceuticals, mainly the pure alcaloids, strychnine, quinine and morphine, extracted from raw products. As well he included mineral chemicals, hydrocyanates, iodine and bromide, all supported by newly achieved works, from Pelletier, Caventou and others. Magendie perfectly skilled in animal experimentation, developped and standardized the as far as to evaluate the activity and safety degrees of these new components. It clearly anticipated the evaluation plan determined by the law for the registration of the new drugs in the twentieth century.