多变量观察的患者特异性早期分类。

IF 0.2 4区 生物学 Q4 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Mohamed F Ghalwash, Dušan Ramljak, Zoran Obradović
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引用次数: 11

摘要

时间序列的早期分类问题近年来受到了广泛的关注。在本文中,我们提出了一个模型,我们称之为早期分类模型(ECM),它允许对多变量观察进行早期,准确和患者特定的分类。ECM是隐马尔可夫模型(HMM)和支持向量机(SVM)模型的集成。在我们对其进行测试的数据集上,它获得了非常有希望的结果:在一组基于多发性硬化症患者对药物治疗反应的公开数据集的实验中,ECM平均只使用了40%的时间序列,并且能够优于一些基线模型,这些模型需要完整的时间序列进行分类。在脓毒症治疗数据集上测试的一组实验中,ECM能够超越标准的基于阈值的方法和最先进的多变量时间序列早期分类方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Patient-specific early classification of multivariate observations.

Early classification of time series has been receiving a lot of attention recently. In this paper we present a model, which we call the Early Classification Model (ECM), that allows for early, accurate and patient-specific classification of multivariate observations. ECM is comprised of an integration of the widely used Hidden Markov Model (HMM) and Support Vector Machine (SVM) models. It attained very promising results on the datasets we tested it on: in one set of experiments based on a published dataset of response to drug therapy in Multiple Sclerosis patients, ECM used only an average of 40% of a time series and was able to outperform some of the baseline models, which needed the full time series for classification. In the set of experiments tested on a sepsis therapy dataset, ECM was able to surpass the standard threshold-based method and the state-of-the-art method for early classification of multivariate time series.

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来源期刊
CiteScore
1.00
自引率
0.00%
发文量
0
审稿时长
>12 weeks
期刊介绍: Mining bioinformatics data is an emerging area at the intersection between bioinformatics and data mining. The objective of IJDMB is to facilitate collaboration between data mining researchers and bioinformaticians by presenting cutting edge research topics and methodologies in the area of data mining for bioinformatics. This perspective acknowledges the inter-disciplinary nature of research in data mining and bioinformatics and provides a unified forum for researchers/practitioners/students/policy makers to share the latest research and developments in this fast growing multi-disciplinary research area.
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