Chih-Chung Yang, Wen-Shin Lin, Chien-Pang Lee, Yungho Leu
{"title":"基因表达与疾病关系的两阶段加权抽样检测策略。","authors":"Chih-Chung Yang, Wen-Shin Lin, Chien-Pang Lee, Yungho Leu","doi":"10.1504/ijdmb.2015.069417","DOIUrl":null,"url":null,"abstract":"<p><p>For microarray data analysis, most of them focus on selecting relevant genes and calculating the classification accuracy by the selected relevant genes. This paper wants to detect the relation between the gene expression levels and the classes of a cancer (or a disease) to assist researchers for initial diagnosis. The proposed method is called a Two Stages Weighted Sampling strategy (TSWS strategy). According to the results, the performance of TSWS strategy is better than other existing methods in terms of the classification accuracy and the number of selected relevant genes. Furthermore, TSWS strategy also can use to understand and detect the relation between the gene expression levels and the classes of a cancer (or a disease).</p>","PeriodicalId":54964,"journal":{"name":"International Journal of Data Mining and Bioinformatics","volume":"12 2","pages":"207-23"},"PeriodicalIF":0.2000,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1504/ijdmb.2015.069417","citationCount":"2","resultStr":"{\"title\":\"Two stages weighted sampling strategy for detecting the relation between gene expression and disease.\",\"authors\":\"Chih-Chung Yang, Wen-Shin Lin, Chien-Pang Lee, Yungho Leu\",\"doi\":\"10.1504/ijdmb.2015.069417\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>For microarray data analysis, most of them focus on selecting relevant genes and calculating the classification accuracy by the selected relevant genes. This paper wants to detect the relation between the gene expression levels and the classes of a cancer (or a disease) to assist researchers for initial diagnosis. The proposed method is called a Two Stages Weighted Sampling strategy (TSWS strategy). According to the results, the performance of TSWS strategy is better than other existing methods in terms of the classification accuracy and the number of selected relevant genes. Furthermore, TSWS strategy also can use to understand and detect the relation between the gene expression levels and the classes of a cancer (or a disease).</p>\",\"PeriodicalId\":54964,\"journal\":{\"name\":\"International Journal of Data Mining and Bioinformatics\",\"volume\":\"12 2\",\"pages\":\"207-23\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2015-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1504/ijdmb.2015.069417\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Data Mining and Bioinformatics\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1504/ijdmb.2015.069417\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MATHEMATICAL & COMPUTATIONAL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Data Mining and Bioinformatics","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1504/ijdmb.2015.069417","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MATHEMATICAL & COMPUTATIONAL BIOLOGY","Score":null,"Total":0}
Two stages weighted sampling strategy for detecting the relation between gene expression and disease.
For microarray data analysis, most of them focus on selecting relevant genes and calculating the classification accuracy by the selected relevant genes. This paper wants to detect the relation between the gene expression levels and the classes of a cancer (or a disease) to assist researchers for initial diagnosis. The proposed method is called a Two Stages Weighted Sampling strategy (TSWS strategy). According to the results, the performance of TSWS strategy is better than other existing methods in terms of the classification accuracy and the number of selected relevant genes. Furthermore, TSWS strategy also can use to understand and detect the relation between the gene expression levels and the classes of a cancer (or a disease).
期刊介绍:
Mining bioinformatics data is an emerging area at the intersection between bioinformatics and data mining. The objective of IJDMB is to facilitate collaboration between data mining researchers and bioinformaticians by presenting cutting edge research topics and methodologies in the area of data mining for bioinformatics. This perspective acknowledges the inter-disciplinary nature of research in data mining and bioinformatics and provides a unified forum for researchers/practitioners/students/policy makers to share the latest research and developments in this fast growing multi-disciplinary research area.