单链 RNA 的球状状态：二级结构重排的影响。

IF 1.3 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Journal of Nucleic Acids Pub Date : 2015-01-01 Epub Date: 2015-08-09 DOI:10.1155/2015/295264

Zareh A Grigoryan, Armen T Karapetian

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引用次数: 0

摘要

通过分析计算研究了在近似粗粒度模型中二级结构的缓慢重排和长单链 RNA（ssRNA）的快速塌缩的相互影响。假设二级结构重排的特征时间远远长于三级结构形成的特征时间。观察到了二阶非平衡相变。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The Globular State of the Single-Stranded RNA: Effect of the Secondary Structure Rearrangements.

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The Globular State of the Single-Stranded RNA: Effect of the Secondary Structure Rearrangements.

The mutual influence of the slow rearrangements of secondary structure and fast collapse of the long single-stranded RNA (ssRNA) in approximation of coarse-grained model is studied with analytic calculations. It is assumed that the characteristic time of the secondary structure rearrangement is much longer than that for the formation of the tertiary structure. A nonequilibrium phase transition of the 2nd order has been observed.

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来源期刊

Journal of Nucleic Acids BIOCHEMISTRY & MOLECULAR BIOLOGY-

CiteScore

3.10

自引率

21.70%

发文量

审稿时长

12 weeks