M Josephine Lusk, Ruby N N Uddin, Monica M Lahra, Frances L Garden, Ratan L Kundu, Pam Konecny
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引用次数: 0
摘要
我们旨在描述 2008-2012 年澳大利亚悉尼两家性传播疾病诊所中异性感染淋病奈瑟菌(NG)的性行为特征。在167例淋病病例中,102例为异性感染,异性感染率呈上升趋势,从2008年的1.1%(95% CI 0.6-2.1)升至2012年的3.0%(95% CI 2.0-4.0)(P = 0.027)。在异性恋男性病例中,21/69(30.4%)的病例可能通过无保护口交感染了 NG,28/69(40.6%)的病例可能通过商业性工作接触感染了 NG。总体而言,商业性工作者的 NG 感染率(2.2%)并未显著高于非商业性工作者(1.2%)(P = 0.15),但 2012 年,商业性工作者的 NG 感染率(8.6%)显著高于非商业性工作者(1.6%)(P < 0.001)。9/33(27.3%)名女性病例中发现了咽部 NG。2.5%的 NG 分离物对头孢曲松的敏感性降低(MIC ≥ 0.03 mg/L),其中无异性感染。所有病例均对阿奇霉素敏感。据报道,在澳大利亚城市性病诊所中,异性淋病的发病率呈明显上升趋势。我们主张继续对妇女进行 NG 筛查,包括对所有更换伴侣并报告有口交行为的妇女进行咽部筛查,因为咽部 NG 可能是异性传播的重要贮存库。应加强对民间社会工作者的宣传。
Pharyngeal Gonorrhoea in Women: An Important Reservoir for Increasing Neisseria gonorrhoea Prevalence in Urban Australian Heterosexuals?
We aim to characterize sexual behavioral aspects of heterosexual Neisseria gonorrhoea (NG) acquisition in two Sexually Transmitted Diseases clinics in Sydney, Australia, in 2008-2012. Of 167 NG cases, 102 were heterosexually acquired with a trend of increasing NG prevalence in heterosexuals from 1.1% (95% CI 0.6-2.1) in 2008 to 3.0% (95% CI 2.0-4.0) in 2012 (P = 0.027). Of heterosexual male cases, unprotected fellatio was the likely sexual activity for NG acquisition in 21/69 (30.4%) and commercial sex work (CSW) contact the likely source in 28/69 (40.6%). NG prevalence overall in CSW (2.2%) was not significantly higher than in non-CSW (1.2%) (P = 0.15), but in 2012 there was a significant increase in NG prevalence in CSW (8.6%) compared to non-CSW (1.6%) (P < 0.001). Pharyngeal NG was found in 9/33 (27.3%) female cases. Decreased susceptibility to ceftriaxone (MIC ≥ 0.03 mg/L) occurred in 2.5% NG isolates, none heterosexually acquired. All were azithromycin susceptible. A significant trend of increasing prevalence of heterosexual gonorrhoea in an urban Australian STD clinic setting is reported. We advocate maintenance of NG screening in women, including pharyngeal screening in all women with partner change who report fellatio, as pharyngeal NG may be an important reservoir for heterosexual transmission. Outreach to CSW should be enhanced.