心血管给药系统的耦合非菲克模型

Mathematical medicine and biology : a journal of the IMA Pub Date : 2016-09-01 DOI:10.1093/imammb/dqv023

J. A. Ferreira;J. Naghipoor;Paula de Oliveira

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引用次数: 12

摘要

提出了一种利用可生物降解药物洗脱支架的心血管药物输送系统的耦合非菲克模型。数值结果采用隐显有限元法得到。分析了血管刚度对洗脱药物在支架内转运的影响。在本文中提出的结果提出了新的观点，以适应药物输送概况，以满足患者的需要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A coupled non-Fickian model of a cardiovascular drug delivery system

A coupled non-Fickian model of a cardiovascular drug delivery system using a biodegradable drug-eluting stent is proposed. The numerical results are obtained using an implicit–explicit finite-element method. The influence of vessel stiffness on the transport of drug eluted from the stent is analysed. The results presented in this paper suggest new perspectives to adapt the drug delivery profile to the needs of the patient.

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Mathematical medicine and biology : a journal of the IMA

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