塞尔维亚猪中首次记录到导致粘菌素耐药性的mcr-1基因:我们应该担心吗?

IF 0.8 4区农林科学 Q3 VETERINARY SCIENCES

Polish journal of veterinary sciences Pub Date : 2022-09-01 DOI:10.24425/pjvs.2022.142031

G Kozoderović, V Lalošević, T Süli, V Vračar

{"title":"塞尔维亚猪中首次记录到导致粘菌素耐药性的mcr-1基因:我们应该担心吗?","authors":"G Kozoderović, V Lalošević, T Süli, V Vračar","doi":"10.24425/pjvs.2022.142031","DOIUrl":null,"url":null,"abstract":"Colistin is being used as a last-resort drug to treat infections caused by multidrug-resistant (MDR) bacteria in humans. In veterinary medicine, colistin has been used for the treatment and prevention of infectious diseases. In the first study of mcr genes by multiplex PCR in healthy pigs from Serbia, we discovered mcr-1 in 4.85% out of 350 fecal samples. The presence of mcr-1 gene was detected on three farms located less than 100 km apart from each other, predominantly in piglet samples. The results point to the necessity of monitoring of colistin resistance and the mcr genes in food producing animals as well as restricting colistin usage on farms.","PeriodicalId":20366,"journal":{"name":"Polish journal of veterinary sciences","volume":null,"pages":null},"PeriodicalIF":0.8000,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"The first record of mcr-1 gene for colistin resistance in pigs from Serbia: should we be worried?\",\"authors\":\"G Kozoderović, V Lalošević, T Süli, V Vračar\",\"doi\":\"10.24425/pjvs.2022.142031\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Colistin is being used as a last-resort drug to treat infections caused by multidrug-resistant (MDR) bacteria in humans. In veterinary medicine, colistin has been used for the treatment and prevention of infectious diseases. In the first study of mcr genes by multiplex PCR in healthy pigs from Serbia, we discovered mcr-1 in 4.85% out of 350 fecal samples. The presence of mcr-1 gene was detected on three farms located less than 100 km apart from each other, predominantly in piglet samples. The results point to the necessity of monitoring of colistin resistance and the mcr genes in food producing animals as well as restricting colistin usage on farms.\",\"PeriodicalId\":20366,\"journal\":{\"name\":\"Polish journal of veterinary sciences\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2022-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Polish journal of veterinary sciences\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.24425/pjvs.2022.142031\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Polish journal of veterinary sciences","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.24425/pjvs.2022.142031","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}

引用次数: 1

摘要

粘菌素被用作治疗人类多药耐药(MDR)细菌引起的感染的最后手段。在兽医学中，粘菌素已被用于治疗和预防传染病。在塞尔维亚健康猪的首次多重PCR研究中，我们在350份粪便样本中发现4.85%的mcr-1基因。在相距不到100公里的三个农场中检测到mcr-1基因的存在，主要是在仔猪样本中。结果表明，有必要监测食品生产动物的粘菌素耐药性和mcr基因，并限制粘菌素在农场的使用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

The first record of mcr-1 gene for colistin resistance in pigs from Serbia: should we be worried?

Colistin is being used as a last-resort drug to treat infections caused by multidrug-resistant (MDR) bacteria in humans. In veterinary medicine, colistin has been used for the treatment and prevention of infectious diseases. In the first study of mcr genes by multiplex PCR in healthy pigs from Serbia, we discovered mcr-1 in 4.85% out of 350 fecal samples. The presence of mcr-1 gene was detected on three farms located less than 100 km apart from each other, predominantly in piglet samples. The results point to the necessity of monitoring of colistin resistance and the mcr genes in food producing animals as well as restricting colistin usage on farms.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Polish journal of veterinary sciences 农林科学-兽医学

CiteScore

1.40

自引率

0.00%

发文量

审稿时长

12-24 weeks

期刊介绍： Polish Journal of Veterinary Sciences accepts short communications, original papers and review articles from the field of, widely understood, veterinary sciences - basic, clinical, environmental, animal-origin food hygiene, feed hygiene, etc.