药用植物:靶向细胞分裂化合物的潜在来源。

IF 2 Q3 PHARMACOLOGY & PHARMACY
Drug Target Insights Pub Date : 2015-06-15 eCollection Date: 2015-01-01 DOI:10.4137/DTI.S24946
Ihsan N Zulkipli, Sheba R David, Rajan Rajabalaya, Adi Idris
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引用次数: 32

摘要

现代药用植物药物的发现已经提供了针对多种病症和疾病的药理活性化合物,如感染、炎症和癌症。迄今为止,药用植物的天然产物仍然是癌症治疗的坚实来源。在其他特性中,抗癌药物的一个有利特性是它能够阻止不可控的细胞分裂过程,因为癌细胞以其异常的细胞分裂而臭名昭著。从药用植物中提取的药物具有潜在的抗癌活性,它们对细胞分裂的影响是一个有吸引力的和不断增长的治疗靶点。尽管如此,仍有大量未经鉴定的天然产物具有潜在的医学应用前景。这篇综述的目的是修订目前对天然植物产品对细胞分裂的影响的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Medicinal Plants: A Potential Source of Compounds for Targeting Cell Division.

Medicinal Plants: A Potential Source of Compounds for Targeting Cell Division.

Medicinal Plants: A Potential Source of Compounds for Targeting Cell Division.

Medicinal Plants: A Potential Source of Compounds for Targeting Cell Division.

Modern medicinal plant drug discovery has provided pharmacologically active compounds targeted against a multitude of conditions and diseases, such as infection, inflammation, and cancer. To date, natural products from medicinal plants remain a solid niche as a source from which cancer therapies can be derived. Among other properties, one favorable characteristic of an anticancer drug is its ability to block the uncontrollable process of cell division, as cancer cells are notorious for their abnormal cell division. There are numerous other documented works on the potential anticancer activity of drugs derived from medicinal plants, and their effects on cell division are an attractive and growing therapeutic target. Despite this, there remains a vast number of unidentified natural products that are potentially promising sources for medical applications. This mini review aims to revise the current knowledge of the effects of natural plant products on cell division.

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来源期刊
Drug Target Insights
Drug Target Insights PHARMACOLOGY & PHARMACY-
CiteScore
2.70
自引率
0.00%
发文量
5
审稿时长
8 weeks
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