[基于甲烷和异硼烷硫醇的磺胺胺的合成及其膜保护性能]。

Bioorganicheskaia khimiia Pub Date : 2015-01-01

E S Izmest'ev, D V Sudarikov, O G Shevchenko, S A Rubtsova, A V Kutchin

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引用次数: 0

摘要

以甲烷和异硼烷硫醇为原料合成了磺胺胺，收率达85%。在H2O2-和aaph诱导的红细胞溶血模型中发现，亚胺亚胺具有膜保护和抗氧化活性，并抑制脂质过氧化和血红蛋白氧化次生产物的积累。

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[Synthesis and membrane protective properties of sulfanylimines based on neomenthane and isobornane thiols].

Synthesis of sulfanylimines based on neomenthane and isobornane thiol was carried out with yields up to 85%. On the model of H2O2- and AAPH-induced hemolysis of blood erythrocytes it was found that the sulfenimines have membrane protective and antioxidant activities and inhibit the accumulation of secondary products of lipid peroxidation and oxidation of hemoglobin.

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Bioorganicheskaia khimiia

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