19岁妊娠37周急性乙酰水杨酸过量。

NDT Plus Pub Date : 2011-12-01 Epub Date: 2011-09-16 DOI:10.1093/ndtplus/sfr104
Huma Farid, Monica H Wojcik, Kenneth B Christopher
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引用次数: 6

摘要

妊娠期急性水杨酸过量对母亲和胎儿都有潜在的致命性,对重症监护管理提出了独特的挑战。虽然对于摄入有毒水杨酸的成人存在建议的血液透析阈值,但尚不清楚这些阈值是否适用于妊娠患者,特别是考虑到乙酰水杨酸等药物可能穿过胎盘屏障并在胎儿血液中积累。我们描述了一例孕龄~ 37周的妊娠患者,自我报告乙酰水杨酸摄入量为32.5 g,并回顾了妊娠期急性和慢性水杨酸摄入的病例,以确定在这种情况下进行血液透析的临床先例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A 19-year-old at 37 weeks gestation with an acute acetylsalicylic acid overdose.

A 19-year-old at 37 weeks gestation with an acute acetylsalicylic acid overdose.

Acute salicylate overdose in pregnancy is potentially fatal for both the mother and fetus and presents a unique challenge in intensive care management. While suggested thresholds exist for hemodialysis in adults with toxic salicylate ingestion, it is unclear if these thresholds remain appropriate for the gravid patient, particularly given that medications such as acetylsalicylic acid may cross the placental barrier and accumulate in the fetal bloodstream. We describe a case of a gravid patient at ∼37 weeks gestational age with a self-reported acetylsalicylic acid ingestion of 32.5 g and review prior cases of both acute and chronic salicylate ingestion in pregnancy in order to determine the clinical precedent for hemodialysis in this situation.

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