{"title":"医学和护理学校缺乏药理学教育的危险:美国临床药理学学院的政策声明。","authors":"Peter H Wiernik","doi":"10.1002/jcph.539","DOIUrl":null,"url":null,"abstract":"Therapeutics in all subspecialties of medicine has become more complex in recent years for a variety of reasons. Newer pharmaceuticals with greater and potentially serious toxicities are commonly used today for a large number of serious illnesses. Such drugs often interact adversely with food and with many so-called “natural” medicines such as Saint. John’s wort. They may also interact with other drugs, such as those used to treat comorbidities that are outside of the realm of expertise of the physician treating the patient’s most serious problem. Many newer agents need to be given in precise doses based on the patient’s weight or body surface area, and somemust be taken in specific relationship to food intake. Drug dosing in many instances must take into account dietary components, administration of other drugs, and patient genetics. Consequently, correct prescribing of medicines today requires a complete knowledge of the pharmacokinetics, pharmacodynamics, drug–drug interactions, and other aspects of the agent to be prescribed. Unfortunately, there is abundant evidence in the form of prescription errors (paper and electronic) and increasing numbers of hospital admissions for drug toxicity in this country and many others that prescribers are not always sufficiently educated to properly administer and monitor present-day therapeutics. For physicians, nurses, and physician assistants, the lack of sufficient clinical pharmacologic training can often be traced all the way back to undergraduate school.","PeriodicalId":15536,"journal":{"name":"Journal of clinical pharmacology","volume":"55 9","pages":"953-4"},"PeriodicalIF":2.4000,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/jcph.539","citationCount":"27","resultStr":"{\"title\":\"A dangerous lack of pharmacology education in medical and nursing schools: A policy statement from the American College of Clinical Pharmacology.\",\"authors\":\"Peter H Wiernik\",\"doi\":\"10.1002/jcph.539\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Therapeutics in all subspecialties of medicine has become more complex in recent years for a variety of reasons. Newer pharmaceuticals with greater and potentially serious toxicities are commonly used today for a large number of serious illnesses. Such drugs often interact adversely with food and with many so-called “natural” medicines such as Saint. John’s wort. They may also interact with other drugs, such as those used to treat comorbidities that are outside of the realm of expertise of the physician treating the patient’s most serious problem. Many newer agents need to be given in precise doses based on the patient’s weight or body surface area, and somemust be taken in specific relationship to food intake. Drug dosing in many instances must take into account dietary components, administration of other drugs, and patient genetics. Consequently, correct prescribing of medicines today requires a complete knowledge of the pharmacokinetics, pharmacodynamics, drug–drug interactions, and other aspects of the agent to be prescribed. Unfortunately, there is abundant evidence in the form of prescription errors (paper and electronic) and increasing numbers of hospital admissions for drug toxicity in this country and many others that prescribers are not always sufficiently educated to properly administer and monitor present-day therapeutics. For physicians, nurses, and physician assistants, the lack of sufficient clinical pharmacologic training can often be traced all the way back to undergraduate school.\",\"PeriodicalId\":15536,\"journal\":{\"name\":\"Journal of clinical pharmacology\",\"volume\":\"55 9\",\"pages\":\"953-4\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2015-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1002/jcph.539\",\"citationCount\":\"27\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of clinical pharmacology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/jcph.539\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2015/6/18 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of clinical pharmacology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/jcph.539","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2015/6/18 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
A dangerous lack of pharmacology education in medical and nursing schools: A policy statement from the American College of Clinical Pharmacology.
Therapeutics in all subspecialties of medicine has become more complex in recent years for a variety of reasons. Newer pharmaceuticals with greater and potentially serious toxicities are commonly used today for a large number of serious illnesses. Such drugs often interact adversely with food and with many so-called “natural” medicines such as Saint. John’s wort. They may also interact with other drugs, such as those used to treat comorbidities that are outside of the realm of expertise of the physician treating the patient’s most serious problem. Many newer agents need to be given in precise doses based on the patient’s weight or body surface area, and somemust be taken in specific relationship to food intake. Drug dosing in many instances must take into account dietary components, administration of other drugs, and patient genetics. Consequently, correct prescribing of medicines today requires a complete knowledge of the pharmacokinetics, pharmacodynamics, drug–drug interactions, and other aspects of the agent to be prescribed. Unfortunately, there is abundant evidence in the form of prescription errors (paper and electronic) and increasing numbers of hospital admissions for drug toxicity in this country and many others that prescribers are not always sufficiently educated to properly administer and monitor present-day therapeutics. For physicians, nurses, and physician assistants, the lack of sufficient clinical pharmacologic training can often be traced all the way back to undergraduate school.
期刊介绍:
The Journal of Clinical Pharmacology (JCP) is a Human Pharmacology journal designed to provide physicians, pharmacists, research scientists, regulatory scientists, drug developers and academic colleagues a forum to present research in all aspects of Clinical Pharmacology. This includes original research in pharmacokinetics, pharmacogenetics/pharmacogenomics, pharmacometrics, physiologic based pharmacokinetic modeling, drug interactions, therapeutic drug monitoring, regulatory sciences (including unique methods of data analysis), special population studies, drug development, pharmacovigilance, womens’ health, pediatric pharmacology, and pharmacodynamics. Additionally, JCP publishes review articles, commentaries and educational manuscripts. The Journal also serves as an instrument to disseminate Public Policy statements from the American College of Clinical Pharmacology.