特发性全身性癫痫的抗癫痫药物选择:阿联酋经验。

Epilepsy research and treatment Pub Date : 2015-01-01 Epub Date: 2015-05-20 DOI:10.1155/2015/184928
Taoufik Alsaadi, Haytham Taha, Fatema Al Hammadi
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引用次数: 4

摘要

我们回顾性地回顾了2005-2010年脑电图实验室患者的脑电图(EEG)报告,以确定从癫痫诊所转介的患者,根据脑电图标准确诊为特发性广泛性癫痫(IGE)。我们试图报告我们在阿联酋的经验,即在癫痫转诊诊所进行评估之前,IGE患者被放置非特异性抗癫痫药物(aed)的频率。109例患者经脑电图诊断为IGE。初诊时,32.11%的患者仅使用广谱(特异性)抗炎药,25.69%的患者使用窄谱(非特异性)抗炎药,15.59%的患者使用各种组合抗炎药。在接受非特异性aed治疗的患者中,35.71%的患者无癫痫发作,64.28%的患者控制不良,导致“伪顽固性状态”。当转换为广谱(特异性)aed时,50%得到良好控制。此外,26.6%的患者在就诊前未使用AED,但在使用特定AED后病情得到了很好的控制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Choice of Antiepileptic Drugs in Idiopathic Generalized Epilepsy: UAE Experience.

We retrospectively reviewed the electroencephalogram (EEG) reports of patients at our EEG lab from the years 2005-2010 to identify patients referred from the epilepsy clinic, with a confirmed diagnosis of idiopathic generalized epilepsy (IGE) by EEG criteria. We sought to report our experience in UAE of how often patients with IGE are placed on nonspecific antiepileptic drugs (AEDs) before being evaluated at an epilepsy referral clinic. 109 patients with a confirmed diagnosis of IGE based on EEG criteria were identified. When initially seen, 32.11% were taking a broad-spectrum (specific) AED only, 25.69% were taking a narrow-spectrum (nonspecific) AED, and 15.59% were placed on various combinations. Of the total patients who were receiving nonspecific AEDs, 35.71% were seizure-free and 64.28% were poorly controlled accounting for "pseudointractability status." When converted to broad-spectrum (specific) AEDs, 50% became well controlled. Furthermore, 26.6% of patients, who were previously on no AED prior to the clinic visit, became well controlled once placed on specific AED.

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