{"title":"IgG4-Related疾病。","authors":"Hisanori Umehara, Mitsuhiro Kawano","doi":"10.6092/1590-8577/2945","DOIUrl":null,"url":null,"abstract":"Immunoglobulin G4-related disease (IgG4-RD) is a multisystem disorder characterized histologically by an IgG4-positive lymphoplasmacytic tissue infiltrate, storiform fibrosis and an obliterative phlebitis. The HISORt criteria can be used to establish the diagnosis and incorporate a multidisciplinary approach, involving histology, radiology, serum IgG4 concentrations and response to corticosteroid therapy. IgG4-related sclerosing cholangitis (IgG4-SC) is the biliary manifestation of the disease, which often occurs in association with autoimmune pancreatitis (AIP).","PeriodicalId":47280,"journal":{"name":"Journal of the Pancreas","volume":"16 2","pages":"217"},"PeriodicalIF":0.1000,"publicationDate":"2015-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"IgG4-Related Disease.\",\"authors\":\"Hisanori Umehara, Mitsuhiro Kawano\",\"doi\":\"10.6092/1590-8577/2945\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Immunoglobulin G4-related disease (IgG4-RD) is a multisystem disorder characterized histologically by an IgG4-positive lymphoplasmacytic tissue infiltrate, storiform fibrosis and an obliterative phlebitis. The HISORt criteria can be used to establish the diagnosis and incorporate a multidisciplinary approach, involving histology, radiology, serum IgG4 concentrations and response to corticosteroid therapy. IgG4-related sclerosing cholangitis (IgG4-SC) is the biliary manifestation of the disease, which often occurs in association with autoimmune pancreatitis (AIP).\",\"PeriodicalId\":47280,\"journal\":{\"name\":\"Journal of the Pancreas\",\"volume\":\"16 2\",\"pages\":\"217\"},\"PeriodicalIF\":0.1000,\"publicationDate\":\"2015-03-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the Pancreas\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.6092/1590-8577/2945\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Pancreas","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6092/1590-8577/2945","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
Immunoglobulin G4-related disease (IgG4-RD) is a multisystem disorder characterized histologically by an IgG4-positive lymphoplasmacytic tissue infiltrate, storiform fibrosis and an obliterative phlebitis. The HISORt criteria can be used to establish the diagnosis and incorporate a multidisciplinary approach, involving histology, radiology, serum IgG4 concentrations and response to corticosteroid therapy. IgG4-related sclerosing cholangitis (IgG4-SC) is the biliary manifestation of the disease, which often occurs in association with autoimmune pancreatitis (AIP).