过敏性支气管肺曲菌病表现为肺大叶或全肺萎陷。

Raj Kumar, Mohammed Noufal Poongadan, Mandeep Singh
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引用次数: 12

摘要

简介:过敏性支气管肺曲霉病(ABPA)是一种t辅助细胞2 (Th2)介导的对曲霉反应的超敏性肺部疾病,通常影响哮喘和囊性纤维化(CF)患者。ABPA很少表现为肺萎陷,这种表现在非哮喘患者中非常罕见。我们提出了一系列的三个病例,其中ABPA表现为大叶性或全肺塌陷。ABPA表现为不透明的半胸是罕见的,只有少数文献报道。病例系列:第一个病例描述的是一个45岁的非吸烟者,病史提示支气管哮喘,胸片检查发现有不透明的右半胸。第二例为62岁非吸烟非哮喘患者,表现为左肺萎陷。最后一例为哮喘男性中肺叶塌陷。所有病例最终证实为ABPA,治疗后临床和放射学均有明显改善。结论:目前的病例系列强调需要积极的方法来诊断这种可治疗的情况下,表现为节段性或全肺萎陷。如果及早发现,预后良好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Allergic bronchopulmonary aspergillosis presenting as lobar or total lung collapse.

Introduction: Allergic bronchopulmonary aspergillosis (ABPA) is a T-helper cell 2 (Th2) mediated hypersensitive lung disorder in response to Aspergillus that usually affects asthmatic and cystic fibrosis (CF) patients. ABPA rarely presents as lung collapse and such kind of presentation is very rare in non asthmatic patients. We are presenting a series of three cases in which ABPA presented as lobar or total lung collapse. ABPA presenting as opaque hemithorax is a rarity with only a few of them reported in the literature.

Case series: the first case described is a 45-year non-smoker with history suggestive of bronchial asthma and on chest radiological examination was found to have opaque right hemithorax. The second case is of 62-year non-smoker non-asthmatic patient who presented to us as left lung collapse. The last case is of middle lobe collapse in asthmatic male. All cases ultimately were proved to be having ABPA and after treatment showed marked clinical and radiological improvement.

Conclusions: The present case series highlights the need for aggressive approach in diagnosing this treatable condition in cases presenting as segmental or total lung collapse. The condition has a good prognosis if detected early.

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