{"title":"肝移植再灌注后纤维蛋白溶解","authors":"Kin-Shing Poon , Chia-Chen Chen , Ashok Thorat , Yi-Ying Chiang , Long-Bin Jeng , Horng-Ren Yang , Te-Hung Chen , Chun-Chieh Yeh , Kuen-Bao Chen","doi":"10.1016/j.aat.2014.12.001","DOIUrl":null,"url":null,"abstract":"<div><p>From September 2012 to March 2013, a total of 63 adult-to-adult living donor liver transplantations were performed at our institution. All the patients were monitored for their coagulation functions using rotation thromboelastometry (ROTEM, Tem Innovations GmbH) during the procedure at the following points: preoperative baseline, 5 minutes, 30 minutes, and 120 minutes, respectively, after reperfusion of the liver graft. A total of 84.13% of cases (<em>n</em> = 53) revealed fibrinolysis after reperfusion of the graft and the condition was reversed after 30 minutes without any need for additional treatment. No significant coagulopathy was observed during this period in all of the cases. The result of the ROTEM finding must correlate with the clinical situation before instituting any management to avoid the risk of thrombosis of the hepatic artery.</p></div>","PeriodicalId":87042,"journal":{"name":"Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists","volume":"53 1","pages":"Pages 41-43"},"PeriodicalIF":0.0000,"publicationDate":"2015-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.aat.2014.12.001","citationCount":"26","resultStr":"{\"title\":\"Fibrinolysis after reperfusion of liver graft\",\"authors\":\"Kin-Shing Poon , Chia-Chen Chen , Ashok Thorat , Yi-Ying Chiang , Long-Bin Jeng , Horng-Ren Yang , Te-Hung Chen , Chun-Chieh Yeh , Kuen-Bao Chen\",\"doi\":\"10.1016/j.aat.2014.12.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>From September 2012 to March 2013, a total of 63 adult-to-adult living donor liver transplantations were performed at our institution. All the patients were monitored for their coagulation functions using rotation thromboelastometry (ROTEM, Tem Innovations GmbH) during the procedure at the following points: preoperative baseline, 5 minutes, 30 minutes, and 120 minutes, respectively, after reperfusion of the liver graft. A total of 84.13% of cases (<em>n</em> = 53) revealed fibrinolysis after reperfusion of the graft and the condition was reversed after 30 minutes without any need for additional treatment. No significant coagulopathy was observed during this period in all of the cases. The result of the ROTEM finding must correlate with the clinical situation before instituting any management to avoid the risk of thrombosis of the hepatic artery.</p></div>\",\"PeriodicalId\":87042,\"journal\":{\"name\":\"Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists\",\"volume\":\"53 1\",\"pages\":\"Pages 41-43\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.aat.2014.12.001\",\"citationCount\":\"26\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1875459714001143\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1875459714001143","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 26
摘要
2012年9月至2013年3月，我院共施行成人对成人活体肝移植63例。所有患者在手术过程中使用旋转血栓弹性测量仪(ROTEM, Tem Innovations GmbH)在以下时间点监测凝血功能:术前基线，肝移植再灌注后5分钟，30分钟和120分钟。总共84.13%的病例(n = 53)在移植物再灌注后出现纤维蛋白溶解，30分钟后病情逆转，无需任何额外治疗。所有病例在此期间均未见明显凝血功能障碍。为了避免肝动脉血栓形成的风险，在采取任何治疗措施之前，ROTEM检查的结果必须与临床情况相关联。
From September 2012 to March 2013, a total of 63 adult-to-adult living donor liver transplantations were performed at our institution. All the patients were monitored for their coagulation functions using rotation thromboelastometry (ROTEM, Tem Innovations GmbH) during the procedure at the following points: preoperative baseline, 5 minutes, 30 minutes, and 120 minutes, respectively, after reperfusion of the liver graft. A total of 84.13% of cases (n = 53) revealed fibrinolysis after reperfusion of the graft and the condition was reversed after 30 minutes without any need for additional treatment. No significant coagulopathy was observed during this period in all of the cases. The result of the ROTEM finding must correlate with the clinical situation before instituting any management to avoid the risk of thrombosis of the hepatic artery.
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