{"title":"空间TT角测量复极化不稳定性。","authors":"Larisa G Tereshchenko","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Aims: </strong>Increased T peaks cloud volume is associated with increased risk of ventricular arrhythmias (VA) in cardiomyopathy (CM) patients. T peaks cloud volume is formed, as a result, of (1) the angle between consecutive T-vectors and (2) temporal variability in T-vector amplitude. This study compares association of these two factors with VA.</p><p><strong>Methods: </strong>Baseline orthogonal ECGs were recorded during 5 min at rest in 414 patients with structural heart disease [mean age 59.4±12.0; 68% whites; 73% men; 45% non-ischemic CM] before implantation of implantable cardioverter-defibrillator (ICD) for primary prevention of sudden cardiac death. The spatial TT' angle between consecutive spatial T vectors was calculated using the definition of the inner product.</p><p><strong>Results: </strong>During a median 14 months of follow-up, 61 patients experienced sustained VA with appropriate ICD therapies. In a multivariable Cox regression model after adjustment for age, sex, race, spatial TT' angle was associated with VA (HR 1.03; 95%CI 1.0-1.05; P=0.034). Interaction with CM type was found: TT' angle was strongly associated with polymorphic VT/VF in non-ischemic CM (HR 1.04; 95%CI 1.0-1.05; P=0.033).</p><p><strong>Conclusion: </strong>Increased spatial TT' angle is associated with increased risk of VA.</p>","PeriodicalId":72683,"journal":{"name":"Computing in cardiology","volume":"41 ","pages":"181-184"},"PeriodicalIF":0.0000,"publicationDate":"2014-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275103/pdf/nihms645028.pdf","citationCount":"0","resultStr":"{\"title\":\"Repolarization Lability Measured by Spatial TT' Angle.\",\"authors\":\"Larisa G Tereshchenko\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aims: </strong>Increased T peaks cloud volume is associated with increased risk of ventricular arrhythmias (VA) in cardiomyopathy (CM) patients. T peaks cloud volume is formed, as a result, of (1) the angle between consecutive T-vectors and (2) temporal variability in T-vector amplitude. This study compares association of these two factors with VA.</p><p><strong>Methods: </strong>Baseline orthogonal ECGs were recorded during 5 min at rest in 414 patients with structural heart disease [mean age 59.4±12.0; 68% whites; 73% men; 45% non-ischemic CM] before implantation of implantable cardioverter-defibrillator (ICD) for primary prevention of sudden cardiac death. The spatial TT' angle between consecutive spatial T vectors was calculated using the definition of the inner product.</p><p><strong>Results: </strong>During a median 14 months of follow-up, 61 patients experienced sustained VA with appropriate ICD therapies. In a multivariable Cox regression model after adjustment for age, sex, race, spatial TT' angle was associated with VA (HR 1.03; 95%CI 1.0-1.05; P=0.034). Interaction with CM type was found: TT' angle was strongly associated with polymorphic VT/VF in non-ischemic CM (HR 1.04; 95%CI 1.0-1.05; P=0.033).</p><p><strong>Conclusion: </strong>Increased spatial TT' angle is associated with increased risk of VA.</p>\",\"PeriodicalId\":72683,\"journal\":{\"name\":\"Computing in cardiology\",\"volume\":\"41 \",\"pages\":\"181-184\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2014-09-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275103/pdf/nihms645028.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Computing in cardiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computing in cardiology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Repolarization Lability Measured by Spatial TT' Angle.
Aims: Increased T peaks cloud volume is associated with increased risk of ventricular arrhythmias (VA) in cardiomyopathy (CM) patients. T peaks cloud volume is formed, as a result, of (1) the angle between consecutive T-vectors and (2) temporal variability in T-vector amplitude. This study compares association of these two factors with VA.
Methods: Baseline orthogonal ECGs were recorded during 5 min at rest in 414 patients with structural heart disease [mean age 59.4±12.0; 68% whites; 73% men; 45% non-ischemic CM] before implantation of implantable cardioverter-defibrillator (ICD) for primary prevention of sudden cardiac death. The spatial TT' angle between consecutive spatial T vectors was calculated using the definition of the inner product.
Results: During a median 14 months of follow-up, 61 patients experienced sustained VA with appropriate ICD therapies. In a multivariable Cox regression model after adjustment for age, sex, race, spatial TT' angle was associated with VA (HR 1.03; 95%CI 1.0-1.05; P=0.034). Interaction with CM type was found: TT' angle was strongly associated with polymorphic VT/VF in non-ischemic CM (HR 1.04; 95%CI 1.0-1.05; P=0.033).
Conclusion: Increased spatial TT' angle is associated with increased risk of VA.
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