在聚乙二醇中使用醛丙酮无催化剂合成高生物活性的5-芳基罗丹宁和2,4-噻唑烷二酮衍生物。

International Journal of Medicinal Chemistry Pub Date : 2013-01-01 Epub Date: 2013-02-14 DOI:10.1155/2013/273534

Dhruva Kumar, Suresh Narwal, Jagir S Sandhu

引用次数: 3

摘要

在80°C的聚乙二醇(PEG)中，不使用任何外部催化剂，绿色高效地合成了5-芳基罗丹宁和2,4-噻唑烷二酮衍生物。反应过程简单，反应时间短，所得收率高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Catalyst-free synthesis of highly biologically active 5-arylidene rhodanine and 2,4-thiazolidinedione derivatives using aldonitrones in polyethylene glycol.

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Catalyst-free synthesis of highly biologically active 5-arylidene rhodanine and 2,4-thiazolidinedione derivatives using aldonitrones in polyethylene glycol.

A green, efficient synthesis of 5-arylidene rhodanine and 2,4-thiazolidinedione derivatives without using any external catalyst in polyethylene glycol (PEG) at 80°C has been described. Reaction procedure is very simple, short, and obtained yields are very high.

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来源期刊

International Journal of Medicinal Chemistry CHEMISTRY, MEDICINAL-

自引率

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发文量

期刊介绍： International Journal of Medicinal Chemistry is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of chemistry associated with drug discovery, design, and synthesis. International Journal of Medicinal Chemistry is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of chemistry associated with drug discovery, design, and synthesis.