{"title":"正电子发射断层成像技术在药物开发中的应用。","authors":"Sibaprasad Bhattacharyya","doi":"10.4172/2167-0501.1000e128","DOIUrl":null,"url":null,"abstract":"Positron Emission Tomography (PET) is a clinically established noninvasive imaging modality. In PET, targeting ligands, or drug molecules labeled with a positron-emitting isotope, typically known as PET-radiopharmaceuticals, are introduced in to the body at a very low concentration (nanomolar or picomolar range), and are not intended to have any pharmacological effect.","PeriodicalId":8764,"journal":{"name":"Biochemistry & Pharmacology: Open Access","volume":"1 ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2012-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2167-0501.1000e128","citationCount":"12","resultStr":"{\"title\":\"Application of Positron Emission Tomography in Drug Development.\",\"authors\":\"Sibaprasad Bhattacharyya\",\"doi\":\"10.4172/2167-0501.1000e128\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Positron Emission Tomography (PET) is a clinically established noninvasive imaging modality. In PET, targeting ligands, or drug molecules labeled with a positron-emitting isotope, typically known as PET-radiopharmaceuticals, are introduced in to the body at a very low concentration (nanomolar or picomolar range), and are not intended to have any pharmacological effect.\",\"PeriodicalId\":8764,\"journal\":{\"name\":\"Biochemistry & Pharmacology: Open Access\",\"volume\":\"1 \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-08-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.4172/2167-0501.1000e128\",\"citationCount\":\"12\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biochemistry & Pharmacology: Open Access\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4172/2167-0501.1000e128\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochemistry & Pharmacology: Open Access","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2167-0501.1000e128","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Application of Positron Emission Tomography in Drug Development.
Positron Emission Tomography (PET) is a clinically established noninvasive imaging modality. In PET, targeting ligands, or drug molecules labeled with a positron-emitting isotope, typically known as PET-radiopharmaceuticals, are introduced in to the body at a very low concentration (nanomolar or picomolar range), and are not intended to have any pharmacological effect.
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