{"title":"奥氮平治疗精神分裂症患者的GIPR基因多态性与体重增加","authors":"Shin Ono, Yutaro Suzuki, Naoki Fukui, Kazushi Sawamura, Takuro Sugai, Junzo Watanabe, Nobuto Tsuneyama, Toshiyuki Someya","doi":"10.1176/appi.neuropsych.13120389","DOIUrl":null,"url":null,"abstract":"<p><p>Association between gastric inhibitory polypeptide receptor polymorphism, rs10423928, and body mass index in olanzapine-treated schizophrenia was examined. Body mass index change for the A/T+A/A genotypes was significantly higher than that for the T/T genotype. rs10423928 may predict weight gain in schizophrenia. </p>","PeriodicalId":514751,"journal":{"name":"The Journal of Neuropsychiatry and Clinical Neurosciences","volume":" ","pages":"162-4"},"PeriodicalIF":0.0000,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1176/appi.neuropsych.13120389","citationCount":"8","resultStr":"{\"title\":\"GIPR Gene Polymorphism and Weight Gain in Patients With Schizophrenia Treated With Olanzapine.\",\"authors\":\"Shin Ono, Yutaro Suzuki, Naoki Fukui, Kazushi Sawamura, Takuro Sugai, Junzo Watanabe, Nobuto Tsuneyama, Toshiyuki Someya\",\"doi\":\"10.1176/appi.neuropsych.13120389\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Association between gastric inhibitory polypeptide receptor polymorphism, rs10423928, and body mass index in olanzapine-treated schizophrenia was examined. Body mass index change for the A/T+A/A genotypes was significantly higher than that for the T/T genotype. rs10423928 may predict weight gain in schizophrenia. </p>\",\"PeriodicalId\":514751,\"journal\":{\"name\":\"The Journal of Neuropsychiatry and Clinical Neurosciences\",\"volume\":\" \",\"pages\":\"162-4\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1176/appi.neuropsych.13120389\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Journal of Neuropsychiatry and Clinical Neurosciences\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1176/appi.neuropsych.13120389\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Journal of Neuropsychiatry and Clinical Neurosciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1176/appi.neuropsych.13120389","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
GIPR Gene Polymorphism and Weight Gain in Patients With Schizophrenia Treated With Olanzapine.
Association between gastric inhibitory polypeptide receptor polymorphism, rs10423928, and body mass index in olanzapine-treated schizophrenia was examined. Body mass index change for the A/T+A/A genotypes was significantly higher than that for the T/T genotype. rs10423928 may predict weight gain in schizophrenia.
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