活体肾脏捐赠的激励机制:为什么我们不能同意进行试验?

Clinical transplants Pub Date : 2013-01-01
Arthur J Matas
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摘要

在1980年,当等待一个标准标准的捐赠肾(年轻的创伤受害者)大约一年的时候,几乎没有理由考虑捐赠的动机。然而,在今天的美国,有超过10万的候选人在等待一个已故捐赠者的肾脏移植。然而,尽管多次尝试提高捐赠率,但在过去7年里并没有增加。因此,等候名单和由此产生的等候时间继续增加,导致等候期间死亡人数增加(或因并发疾病而从名单上除名)。人们对激励措施提出了一些担忧。然而,真正的问题是,总的来说,这些担忧是否证明继续禁止激励(以及由此导致的每年数千人死亡)是合理的,或者我们是否应该开展激励试验,以确定激励是否会增加捐赠,同时不增加短期和长期捐赠者或接受者的风险,而不是今天的传统捐赠?
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A regulated system of incentives for living kidney donation: why can't we agree to do a trial?

In 1980, when there was approximately a one-year wait for a standard criteria donor kidney (young trauma victim), there was little rationale for considering incentives for donation. Today, however, in the United States, there are over 100,000 candidates on the waiting list for a deceased donor kidney transplant. Yet, in spite of numerous attempts to increase the donation rate, there has not been an increase in the last seven years. As a result, the waiting list and the resultant waiting time continue to grow, leading to an increased number of deaths (or removals from the list because of development of comorbidity) while waiting. A number of concerns have been raised about incentives. However, the real question is that - on balance - do these concerns justify continuing a ban on incentives (and the resultant thousands of deaths per year) or should we develop trials of incentives to determine whether or not incentives increase donation while simultaneously not increasing short- and long-term donor or recipient risks over those seen with today's conventional donation?

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