类风湿关节炎和骨关节炎患者感染髋关节置换术中的细菌发现:挪威关节置换术登记报告的318例感染修订研究。

ISRN orthopedics Pub Date : 2012-10-17 eCollection Date: 2012-01-01 DOI:10.5402/2012/437675
J C Schrama, O Lutro, H Langvatn, G Hallan, B Espehaug, H Sjursen, L B Engesaeter, B-T Fevang
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引用次数: 9

摘要

据报道,在类风湿关节炎(RA)的假体关节感染(PJI)中,金黄色葡萄球菌的发病率很高。类风湿关节炎患者被认为有可能感染口腔或牙齿来源的细菌的高风险。从1987年到2007年,挪威关节成形术登记(NAR)报告了1443例感染的修订。本研究以255例OA患者269次感染为对照组。在NAR中,我们从1987年到2009年在37例RA患者中发现了49次感染。RA患者比OA患者平均年轻10岁,女性患者较多(70%对54%)。我们发现RA和OA的细菌检查结果没有差异。与OA患者相比,RA患者中金黄色葡萄球菌引起PJI的频率更高(18%对11%)。RA患者中未发现潜在牙源性细菌,而OA患者中发现了4%。在类风湿关节炎患者THRs感染的修订中发现的细菌与OA患者没有显著差异。RA感染髋关节置换术中未发现口腔或牙源性细菌。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Bacterial findings in infected hip joint replacements in patients with rheumatoid arthritis and osteoarthritis: a study of 318 revisions for infection reported to the norwegian arthroplasty register.

Bacterial findings in infected hip joint replacements in patients with rheumatoid arthritis and osteoarthritis: a study of 318 revisions for infection reported to the norwegian arthroplasty register.

High rates of Staphylococcus aureus are reported in prosthetic joint infection (PJI) in rheumatoid arthritis (RA). RA patients are considered to have a high risk of infection with bacteria of potentially oral or dental origin. One thousand four hundred forty-three revisions for infection were reported to the Norwegian Arthroplasty Register (NAR) from 1987 to 2007. For this study 269 infection episodes in 255 OA patients served as control group. In the NAR we identified 49 infection episodes in 37 RA patients from 1987 to 2009. The RA patients were, on average, 10 years younger than the OA patients and there were more females (70% versus 54%). We found no differences in the bacterial findings in RA and OA. A tendency towards a higher frequency of Staphylococcus aureus (18% versus 11%) causing PJI was found in the RA patients compared to OA. There were no bacteria of potential odontogenic origin found in the RA patients, while we found 4% in OA. The bacteria identified in revisions for infection in THRs in patients with RA did not significantly differ from those in OA. Bacteria of oral or dental origin were not found in infected hip joint replacements in RA.

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