维生素d水平和脊柱手术结果。

ISRN orthopedics Pub Date : 2013-04-11 eCollection Date: 2013-01-01 DOI:10.1155/2013/471695
William J Rodriguez, Jason Gromelski
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引用次数: 20

摘要

在背痛患者中,维生素D缺乏症的患病率很高,无论他们是否需要手术干预。此外,维生素D缺乏症的风险并不局限于具有传统临床危险因素的个体。维生素D在骨骼形成、维护和重塑以及肌肉功能中起着至关重要的作用。已发表的数据表明,维生素D缺乏症会以多种方式对骨骼形成和肌肉功能产生不利影响。文献中包含大量与维生素d缺乏症相关的肌病和/或肌肉骨骼疼痛的报道。就脊柱融合的结果而言,患者在x光片上可能疼痛明显减轻,并且出现新生骨,但其功能能力可能仍然严重受限。维生素D缺乏症可能是这些患者术后持续疼痛的一个因素。事实上,维生素D缺乏症不是无症状的,症状可以独立于与骨软化症等疾病相关的肌肉骨骼病理改变而表现出来。维生素D的状态似乎经常被忽视,有必要提高所有治疗脊柱患者的医疗从业人员对其重要性的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Vitamin d status and spine surgery outcomes.

There is a high prevalence of hypovitaminosis D in patients with back pain regardless of whether or not they require surgical intervention. Furthermore, the risk of hypovitaminosis D is not limited to individuals with traditional clinical risk factors. Vitamin D plays an essential role in bone formation, maintenance, and remodeling, as well as muscle function. Published data indicate that hypovitaminosis D could adversely affect bone formation and muscle function in multiple ways. The literature contains numerous reports of myopathy and/or musculoskeletal pain associated with hypovitaminosis D. In terms of spinal fusion outcomes, a patient may have a significant decrease in pain and the presence of de novo bone on an X-ray, yet their functional ability may remain severely limited. Hypovitaminosis D may be a contributing factor to the persistent postoperative pain experienced by these patients. Indeed, hypovitaminosis D is not asymptomatic, and symptoms can manifest themselves independent of the musculoskeletal pathological changes associated with conditions like osteomalacia. It appears that vitamin D status is routinely overlooked, and there is a need to raise awareness about its importance among all healthcare practitioners who treat spine patients.

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