血栓栓塞作为肾动脉闭塞和急性肾损伤的原因:两周后肾功能恢复。

Case reports in nephrology and urology Pub Date : 2014-04-17 eCollection Date: 2014-01-01 DOI:10.1159/000362538
Niina Koivuviita, Risto Tertti, Maija Heiro, Ilkka Manner, Kaj Metsärinne
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引用次数: 23

摘要

血栓栓塞是一个罕见的原因急性肾损伤(AKI)。它可能导致永久性肾功能丧失。我们的患者患有扩张性心肌病和人工主动脉瓣,由于血栓栓塞性动脉闭塞孤立功能肾脏而出现AKI。延迟2周后,用重组组织型纤溶酶原激活剂进行局部动脉溶栓治疗,但效果不明显。然而,随后的经皮腔内血管成形术与支架置入是成功的。立即开始利尿,2周后肾功能完全恢复。虽然肾脏中没有明显的动脉循环,但我们认为肾主动脉次全闭塞的少量血流使肾脏组织冬眠成为可能,并有助于恢复。因此,即使在长时间缺血后,血运重建也是有用的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Thromboembolism as a cause of renal artery occlusion and acute kidney injury: the recovery of kidney function after two weeks.

Thromboembolism as a cause of renal artery occlusion and acute kidney injury: the recovery of kidney function after two weeks.

Thromboembolic occlusion is a rare cause of acute kidney injury (AKI). It may lead to permanent loss of renal function. Our patient, who had dilated cardiomyopathy and prosthetic aortic valve, presented with AKI due to thromboembolic arterial occlusion of a solitary functioning kidney. After 2 weeks delay, local intra-arterial thrombolytic treatment with recombinant tissue plasminogen activator was performed without sufficient effect. However, a subsequent percutaneous transluminal angioplasty with stenting was successful. Diuresis began immediately, and renal function was fully recovered after 2 weeks. Although there had been no evident arterial circulation in the kidney, we think that minor flow through subtotal occlusion of the main renal artery made the hibernation of kidney tissue possible and contributed to the recovery. Thus, even after prolonged ischemia, revascularization can be useful.

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