麻风病周围神经干减压可防止畸形的发生和发展?

Q4 Medicine
Indian journal of leprosy Pub Date : 2013-10-01
S Husain
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引用次数: 0

摘要

周围神经受累导致麻风病的畸形形成。高剂量(40-60毫克)类固醇和抗麻风病药物是首选,即使70-75%的病例在上述治疗下出现畸形。772根尺神经、120根正中神经、108根胫后神经经12周治疗无效,分别行外、内神经干减压术。对这些病例进行了5-20年的不同时间间隔的随访。所有病例的尺神经、正中神经和胫后神经疼痛(神经炎)均恢复。针刺/羽毛或棉絮触感可使50%的患者感觉完全恢复。20%的患者感觉状态维持术前水平。胫后神经减压术后6个月内足底溃疡愈合。仅6例复发。尺神经整体运动恢复89%,正中神经整体运动恢复70%。感觉恢复恢复保护感觉,防止二次伤害。运动动力的改善改善了手的功能,改善了外观,这在没有手术干预的情况下是不可能的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Decompression of peripheral nerve trunks in leprosy prevents the development and progression of deformities?

Peripheral nerve involvement results in deformities formation in leprosy. High doses of (40-60 mg) steroids along with the anti-leprosy drugs is preferred even though the 70-75% cases develop deformity with the above treatment. 772 ulnar nerves, 120 median nerves and 108 posterior tibial nerves not responding to above medical treatment in 12 weeks, were undertaken for external and internal nerve trunk decompression. These cases were followed-up for 5-20 years at various intervals. The pain in nerves (neuritis) recovered in all cases of ulnar, median and posterior tibial nerves. Full sensory recovery with pin prick/feather or cotton wool touch was seen in 50% cases of all the three nerves. 20% cases maintain the pre-operative levels of sensory status. Plantar ulcers healed within 6 months after decompression of posterior tibial nerve. Only 6 cases showed reoccurrence. Overall motor recovery in ulnar nerve was seen 89% and 70% in median nerve. The sensory recovery restores protective sensation which prevents secondary injuries. The improvement of motor power gave better functional hands and improved the appearance which in absence of surgical intervention was not possible.

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来源期刊
Indian journal of leprosy
Indian journal of leprosy Medicine-Dermatology
CiteScore
0.50
自引率
0.00%
发文量
0
期刊介绍: Indian Journal of Leprosy is one of the oldest journals of India published quarterly by Hind Kusht Nivaran Sangh (Indian Leprosy Association) since 1929. The Journal covers all research aspects of leprosy, tuberculosis and other mycobacterial diseases.
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