PFC在啮齿动物识别记忆提取中的作用

Q Medicine

Journal of Physiology-Paris Pub Date : 2014-09-01 DOI:10.1016/j.jphysparis.2014.03.001

Pedro Bekinschtein , Noelia Weisstaub

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引用次数: 14

摘要

记忆研究的挑战之一是情景记忆的神经生物学研究，情景记忆是由支持事件有意识回忆的所有不同经验组成部分的整合所定义的。情景记忆的特征包括一个特定的物体或人(“什么”)，经历发生的背景(“在哪里”)和事件发生的特定时间(“什么时候”)。尽管情景记忆主要是在人类身上进行的研究，但也有许多研究表明，这些特征也存在于非人类动物身上。在此，我们总结了一系列研究，这些研究采用不同版本的动物识别记忆任务来研究内侧前额叶皮层在情景记忆中的作用。

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Role of PFC during retrieval of recognition memory in rodents

One of the challenges for memory researches is the study of the neurobiology of episodic memory which is defined by the integration of all the different components of experiences that support the conscious recollection of events. The features of episodic memory includes a particular object or person (“what”), the context in which the experience took place (“where”) and the particular time at which the event occurred (“when”). Although episodic memory has been mainly studied in humans, there are many studies that demonstrate these features in non-human animals. Here, we summarize a set of studies that employ different versions of recognition memory tasks in animals to study the role of the medial prefrontal cortex in episodic memory.

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来源期刊

Journal of Physiology-Paris 医学-神经科学

CiteScore

2.02

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Each issue of the Journal of Physiology (Paris) is specially commissioned, and provides an overview of one important area of neuroscience, delivering review and research papers from leading researchers in that field. The content will interest both those specializing in the experimental study of the brain and those working in interdisciplinary fields linking theory and biological data, including cellular neuroscience, mathematical analysis of brain function, computational neuroscience, biophysics of brain imaging and cognitive psychology.