纽约市社区医院乳腺癌术后患者生存和年龄相关结果的种族差异

ISRN oncology Pub Date : 2014-02-12 eCollection Date: 2014-01-01 DOI:10.1155/2014/694591
Stacey Martindale, Awinder Singh, Hua Wang, Ashley Steinberg, Amer Homsi, Haidi Zhang, Alan Go, Peter Pappas
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引用次数: 3

摘要

在过去的二十年里,乳腺癌的存活率有了显著的提高。然而,与白种美国妇女相比,非裔美国妇女的乳腺癌诊断率较低,死亡率仍然较高。本研究的目的是分析可能影响乳腺癌生存的术后事件。这是对从1997年到2010年布鲁克林医院中心癌症登记处前瞻性收集数据的回顾性分析。在登记的1538名患者中,1226名AA患者和269名高加索患者。研究分为两个时间段,1997-2004年(A期)和2005-2010年(B期),以评估治疗结果对生存率的影响。在A期,所有患者、AA女性和高加索女性的5年生存率分别为75.37%、74.53%和78.70%。在b期,这些概率分别增加到87.62%、87.15%和89.99%。AA妇女生存率的提高可能归因于辅助化疗、放疗和激素治疗的使用。白种人患者生存率的提高归功于放射治疗的使用,以及早期检测导致更有利的肿瘤分级和病理分期。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Racial disparities in survival and age-related outcome in postsurgery breast cancer patients in a new york city community hospital.

Breast cancer survival has significantly improved over the past two decades. However, the diagnosis of breast cancer is lower and the mortality rate remains higher, in African American women (AA) compared to Caucasian-American women. The purpose of this investigation is to analyze postoperative events that may affect breast cancer survival. This is a retrospective analysis of prospectively collected data from The Brooklyn Hospital Center cancer registry from 1997 to 2010. Of the 1538 patients in the registry, 1226 are AA and 269 are Caucasian. The study was divided into two time periods, 1997-2004 (period A) and 2005-2010 (period B), in order to assess the effect of treatment outcomes on survival. During period A, 5-year survival probabilities of 75.37%, 74.53%, and 78.70% were seen among all patients, AA women and Caucasian women, respectively. These probabilities increased to 87.62%, 87.15% and 89.99% in period B. Improved survival in AA women may be attributed to the use of adjuvant chemotherapy, radiation, and hormonal therapy. Improved survival in Caucasian patients was attributed to the use of radiation therapy, as well as earlier detection resulting in more favorable tumor grades and pathological stages.

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