成人脊柱侧凸患者在L5处进行脊柱融合术与骶骨延伸术的结果比较。

Zeeshan M Sardar, Jean A Ouellet, Dena J Fischer, Andrea C Skelly
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引用次数: 7

摘要

研究设计系统评价。研究理由:成人脊柱侧凸是一种常见的疾病,与没有脊柱侧凸的人相比,与明显更高的疼痛、功能损害和对生活质量的影响相关。脊柱融合术可量化地改善患者的生活质量。然而,对于接受长腰椎融合术的患者,在L5椎间盘停止融合还是延伸到S1椎间盘,特别是如果L5-S1椎间盘是健康的,仍然存在争议。本研究的目的是评估与骶骨延伸手术相比,在需要脊柱融合手术的成人脊柱侧凸患者中,在L5处停止融合是否会增加翻修、矫正损失和/或功能不良的比较发生率。材料和方法使用PubMed、国家指南信息中心数据库和评估需要脊柱融合手术的成人脊柱侧凸患者的关键文章的参考文献进行系统的文献回顾,并比较骶骨融合与L5处停止的结果。文章是根据预先确定的标准纳入的,并使用预先确定的质量评级方案进行评价。结果从111篇引文中,26篇文章进行了全文综述,3项回顾性队列研究符合所有纳入和排除标准。在两项研究中,腰椎融合至L5的患者翻修率(20.8-23.5%)低于融合至骶骨的患者翻修率(19.0-58.3%)。评估畸形矫正的研究使用了不同的测量方法,使得研究之间的比较变得困难。在两项使用不同测量方法的研究中,没有发现患者报告的功能结果有显著差异。结论:有限的可用数据表明,在比较成人脊柱侧凸患者腰5椎体融合术与骶骨伸入术的研究中,翻修率的差异并没有一致地达到统计学意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Outcomes in adult scoliosis patients who undergo spinal fusion stopping at L5 compared with extension to the sacrum.

Outcomes in adult scoliosis patients who undergo spinal fusion stopping at L5 compared with extension to the sacrum.

Outcomes in adult scoliosis patients who undergo spinal fusion stopping at L5 compared with extension to the sacrum.

Outcomes in adult scoliosis patients who undergo spinal fusion stopping at L5 compared with extension to the sacrum.

Study Design Systematic review. Study Rationale Adult scoliosis is a common disorder that is associated with significantly higher pain, functional impairment, and effect on quality of life than those without scoliosis. Surgical spinal fusion has led to quantifiable improvement in patient's quality of life. However, for patients undergoing long lumbar fusion, the decision to stop the fusion at L5 or to extend to S1, particularly if the L5-S1 disc is healthy, remains controversial. Objective The aim of the study is to evaluate if fusion stopping at L5 increases the comparative rates of revision, correction loss, and/or poor functional outcomes compared with extension to the sacrum in adult scoliosis patients who require spinal fusion surgery. Materials and Methods A systematic review of the literature was performed using PubMed, the National Guideline Clearinghouse Database and bibliographies of key articles that evaluated adult scoliosis patients who required spinal fusion surgery and compared outcomes for fusions to the sacrum versus stopping at L5. Articles were included on the basis of predetermined criteria and were appraised using a predefined quality-rating scheme. Results From 111 citations, 26 articles underwent full-text review, and 3 retrospective cohort studies met all inclusion and exclusion criteria. Revision rates in subjects who underwent spinal fusion to L5 (20.8-23.5%) were lower in two studies compared with those with fusion extending to the sacrum (19.0-58.3%). Studies that assessed deformity correction used different measures, making comparison across studies difficult. No significant differences were found in patient-reported functional outcomes across two studies that used different measures. Conclusion The limited data available suggest that differences in revision rates did not consistently reach statistical significance across studies that compared spinal fusion to L5 versus extension to sacrum in adult scoliosis patients.

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