部分保留IV节段对结直肠癌肝转移患者行扩大右肝切除术无益处。

M G Wiggans, S Fisher, H Adwan, S Aroori, M J Bowles, D A Stell
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引用次数: 1

摘要

介绍。减少切除肝实质的体积可以降低发病率和死亡率。本研究的目的是确定IV节段的部分保留是否会改善结肠直肠癌肝转移(CRLM)的延长右肝切除术的预后。材料与方法。回顾性分析行右侧肝切除术的CRLM患者。比较117例右肝切除术(n = 85)、部分扩大右肝切除术(n = 20)和完全扩大右肝切除术(n = 12)患者的90天死亡率和器官功能障碍率。结果。右肝切除术组90天死亡率(3/85)与扩展右肝切除术组(0/12)相似(P = 1.000),低于部分扩展右肝切除术组(4/20)(P = 0.024)。在接受右肝切除术、部分扩大或扩大肝切除术的患者中,肝功能障碍和肾功能障碍的发生率相似。讨论。保留部分IV节段对CRLM行扩展右肝切除术的临床益处不大。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Partial Preservation of Segment IV Confers No Benefit When Performing Extended Right Hepatectomy for Colorectal Liver Metastases.

Introduction. Reducing the volume of resected liver parenchyma may lead to lower morbidity and mortality. The aim of this study was to determine whether partial preservation of segment IV leads to improved outcomes when undertaking extended right hepatectomy for colorectal liver metastases (CRLM). Materials and Methods. A retrospective analysis of patients undergoing right-sided hepatectomy for CRLM was performed. Rates of 90-day mortality and organ dysfunction were compared in 117 patients undergoing right hepatectomy (n = 85), partially extended right hepatectomy with preservation of part of segment IV (n = 20), and fully extended right hepatectomy (n = 12). Results. The 90-day mortality rate of those undergoing right hepatectomy (3/85) was similar to that of those undergoing extended right hepatectomy (0/12) (P = 1.000) but lower than that of those undergoing partially extended right hepatectomy (4/20) (P = 0.024). The rates of hepatic and renal dysfunction were similar between patients undergoing right hepatectomy, partially extended or extended hepatectomy. Discussion. Preservation of part of segment IV confers little clinical benefit when performing extended right hepatectomy for CRLM.

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