加纳上西部地区艾滋病毒/艾滋病患者抗逆转录病毒治疗依从性的预测因素

ISRN AIDS Pub Date : 2013-12-10 eCollection Date: 2013-01-01 DOI:10.1155/2013/873939
Christian Obirikorang, Peter Kuugemah Selleh, Jubilant Kwame Abledu, Chris Opoku Fofie
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引用次数: 64

摘要

背景。ART干预措施的有效性只有在最大程度的坚持下才能实现。有效抑制艾滋病毒/艾滋病需要接近完美的依从性水平>95%。本研究的主要目的是确定促进艾滋病毒/艾滋病患者坚持抗逆转录病毒治疗的社会人口和社会经济因素。方法。这项描述性横断面研究于2013年3月至5月在华盛顿州上西部地区医院进行。采用结构化问卷对201例接受抗逆转录病毒治疗的HIV 1血清阳性患者(平均年龄36.6±9.9岁)进行访谈。收集的数据使用GraphPad Prism版本5进行分析。的P值
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Predictors of Adherence to Antiretroviral Therapy among HIV/AIDS Patients in the Upper West Region of Ghana.

Predictors of Adherence to Antiretroviral Therapy among HIV/AIDS Patients in the Upper West Region of Ghana.

Background. The effectiveness of ART interventions is only realized in maximal levels of adherence. A near perfect adherence level of >95% is required for the effective suppression of HIV/AIDS virus. The main objective of this study was to identify the sociodemographic and socioeconomic factors that facilitate adherence to antiretroviral therapy among HIV/AIDS patients. Methods. This descriptive cross-sectional study was conducted between March and May 2013 at the Upper West Regional Hospital, Wa. A total of 201 confirmed HIV 1 seropositive subjects (mean age 36.6 ± 9.9 years) receiving antiretroviral therapy were interviewed using a structured questionnaire. The collected data was analyzed using GraphPad Prism version 5. A P value of <0.05 was considered statistically significant for all statistical analyses. Results. Overall lifetime adherence was found to be 62.2% while medication adherence in the last six months, last three months, last month, and last week were 73.6%, 87.1%, 91.0%, and 86.0%, respectively. The study revealed a positive association between adherence to ART and immunological success, with nonadherence increasing the risk (OR (95% CI): 9.2 (3.2-26.9)) of immunological failure. Univariate logistic regression analysis of the data showed that other ailments and side effects of drug were negatively associated with adherence to ART whereas self-perceived wellness, family support, and regular followup were positively associated with adherence to ART. Conclusion. Regular attendance at followup and family support are vital factors for 100% lifetime medication adherence. Effective counseling sessions on adherence for patients on antiretroviral therapy are paramount for the realization of the purpose of antiretroviral therapy programmes in Ghana.

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