基于三联体的 DNA 序列二维图形表示法及其应用。

Sai Zou, Lei Wang, Junfeng Wang
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引用次数: 0

摘要

在本文中,我们首先为 64 个三连串提出了一个新的 "权重 "概念,并为每种三连串定义了不同的权重。然后,我们给出了一种新颖的 DNA 序列二维图形表示法,它可以将 DNA 序列转化为图集,便于对 DNA 序列进行定量比较。之后,结合新设计的相似度量,我们介绍了一种对 DNA 序列进行相似性/不相似性分析的新方法。最后,在对 11 个物种的β-球蛋白基因的完整编码序列进行相似性/不相似性分析时的应用说明了我们新提出的方法的实用性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A 2D graphical representation of the sequences of DNA based on triplets and its application.

A 2D graphical representation of the sequences of DNA based on triplets and its application.

A 2D graphical representation of the sequences of DNA based on triplets and its application.

A 2D graphical representation of the sequences of DNA based on triplets and its application.

In this paper, we first present a new concept of 'weight' for 64 triplets and define a different weight for each kind of triplet. Then, we give a novel 2D graphical representation for DNA sequences, which can transform a DNA sequence into a plot set to facilitate quantitative comparisons of DNA sequences. Thereafter, associating with a newly designed measure of similarity, we introduce a novel approach to make similarities/dissimilarities analysis of DNA sequences. Finally, the applications in similarities/dissimilarities analysis of the complete coding sequences of β-globin genes of 11 species illustrate the utilities of our newly proposed method.

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