[狂犬病病毒在亚洲的进化和传播特征]。

中华实验和临床病毒学杂志 Pub Date : 2013-06-01
Xiao-Yan Tao, Hao Li, Qing Tang, Guo-Dong Liang
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引用次数: 0

摘要

目的:了解中国和亚洲地区狂犬病病毒(RABV)的进化关系,了解亚洲地区狂犬病病毒(RABV)的进化和传播特征。方法:选取中国代表性菌株的G序列,结合亚洲其他国家的G序列,采用BEAST和MigraPhyla软件进行分析。结果:系统发育分析显示,中国6个病毒群(中国ⅰ~ⅵ)具有不同的流行范围:中国ⅰ、ⅱ、ⅴ病毒群在我国刚刚流行;中国VI群,产自广西和云南,与东南亚菌株杂交;中国III群和IV群与亚洲国家菌株也有较近的亲缘关系。结论:泰国和印度可能是亚洲的两个狂犬病传播中心。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Evolutionary and transmission characteristics of rabies viruses in Asia].

Objective: To understand the rabies virus (RABV) evolutionary relationship between the strains of China and Asia and to know the evolution and transmission characteristics of RABV in Asia.

Methods: The G sequences of representative strains from China were selected and combined the sequences of other countries in Asia to analyze using BEAST and MigraPhyla software.

Results: The phylogenetic analysis showed that six groups (China I-VI) of China had different epidemic range: China I , II and V groups just cycled in our country; China VI group, from Guangxi and Yunnan provinces, crossed with Southeast Asian strains; China III group and IV group also have closer genetic relationship with Asian country strains.

Conclusion: Geographic migration in Asia showed that Thailand and India may be two rabies transmission centers in Asia.

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