{"title":"北京市成人肠道病毒71型感染血清流行病学分析","authors":"Jing-Jing Wang, Wei Wu, Hui-Jie Pan","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the enterovirus 71 (EV 71) protective antibody level of health adults people in Beijing.</p><p><strong>Methods: </strong>Serum samples and information of participants were collected from hospitals in Beijing. EV71 IgG was tested by enzyme-linked immunoadsordent assay (ELISA). EV 71 neutralization antibody was evaluated by micro-cytopathic effect neutralization test (MCPENT).</p><p><strong>Results: </strong>486 participants were enrolled. Age range was 19-62 years old. The average EV 71 IgG positive rate was 40. 3% , there are no significant difference between the EV 71 IgG positive rate of male and female. The rate of EV 71 neutralization antibody which title high than 1:256 is 13.3%. The rate of EV 71 IgG and the titile of EV 71 neutralization antibody are decreasing by the age.</p><p><strong>Conclusion: </strong>40% of health adults of Beijing area have EV71 protective antibody. But the title higher than 1:256 is only 13.3%. EV 71 protective antibody decreases significantly with the age.</p>","PeriodicalId":70973,"journal":{"name":"中华实验和临床病毒学杂志","volume":"27 3","pages":"170-2"},"PeriodicalIF":0.0000,"publicationDate":"2013-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Sero-epidemiological analysis for entervirus 71 infection of adults in Beijing].\",\"authors\":\"Jing-Jing Wang, Wei Wu, Hui-Jie Pan\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To evaluate the enterovirus 71 (EV 71) protective antibody level of health adults people in Beijing.</p><p><strong>Methods: </strong>Serum samples and information of participants were collected from hospitals in Beijing. EV71 IgG was tested by enzyme-linked immunoadsordent assay (ELISA). EV 71 neutralization antibody was evaluated by micro-cytopathic effect neutralization test (MCPENT).</p><p><strong>Results: </strong>486 participants were enrolled. Age range was 19-62 years old. The average EV 71 IgG positive rate was 40. 3% , there are no significant difference between the EV 71 IgG positive rate of male and female. The rate of EV 71 neutralization antibody which title high than 1:256 is 13.3%. The rate of EV 71 IgG and the titile of EV 71 neutralization antibody are decreasing by the age.</p><p><strong>Conclusion: </strong>40% of health adults of Beijing area have EV71 protective antibody. But the title higher than 1:256 is only 13.3%. EV 71 protective antibody decreases significantly with the age.</p>\",\"PeriodicalId\":70973,\"journal\":{\"name\":\"中华实验和临床病毒学杂志\",\"volume\":\"27 3\",\"pages\":\"170-2\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2013-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中华实验和临床病毒学杂志\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华实验和临床病毒学杂志","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Sero-epidemiological analysis for entervirus 71 infection of adults in Beijing].
Objective: To evaluate the enterovirus 71 (EV 71) protective antibody level of health adults people in Beijing.
Methods: Serum samples and information of participants were collected from hospitals in Beijing. EV71 IgG was tested by enzyme-linked immunoadsordent assay (ELISA). EV 71 neutralization antibody was evaluated by micro-cytopathic effect neutralization test (MCPENT).
Results: 486 participants were enrolled. Age range was 19-62 years old. The average EV 71 IgG positive rate was 40. 3% , there are no significant difference between the EV 71 IgG positive rate of male and female. The rate of EV 71 neutralization antibody which title high than 1:256 is 13.3%. The rate of EV 71 IgG and the titile of EV 71 neutralization antibody are decreasing by the age.
Conclusion: 40% of health adults of Beijing area have EV71 protective antibody. But the title higher than 1:256 is only 13.3%. EV 71 protective antibody decreases significantly with the age.
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