神经精神疾病中δ, θ, α, β和γ反应振荡的综述。

Erol Başar, Bahar Güntekin
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引用次数: 117

摘要

大脑振荡的方法和概念遍及神经科学文献,特别是在认知过程中。认知障碍患者的电生理变化不仅为临床研究提供了基础知识,也为理解健康受试者的认知过程提供了基础知识。这篇综述包括对精神分裂症、双相情感障碍、轻度认知障碍、阿尔茨海默病和注意缺陷多动障碍的脑振荡的描述。回顾的出版物包括几种方法学方法:自发脑电图(EEG)频谱分析,诱发振荡,事件相关振荡,以及自发脑电图和事件相关振荡的一致性。这篇综述清楚地表明,在研究的所有疾病中,认知障碍都发生了根本性的变化。因此,振荡最有可能用作临床研究中的生物标志物。这篇综述的结论包括一些说明大脑振荡的本质,它们在认知过程中的应用,以及记录大脑振荡在记忆丧失、注意力缺陷和学习中的有用性的评论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Review of delta, theta, alpha, beta, and gamma response oscillations in neuropsychiatric disorders.

Method and concepts of brain oscillations pervade the neuroscience literature, especially in cognitive processes. Electrophysiological changes in patients with cognitive impairment will provide fundamental knowledge, not only for clinical studies but also, in turn, for understanding cognitive processes in healthy subjects. This review includes description of brain oscillations in schizophrenia, bipolar disorder, mild cognitive impairment, Alzheimer's disease, and attention deficit hyperactivity disorder. The reviewed publications include several methodological approaches: analysis of spontaneous electroencephalogram (EEG) spectra, evoked oscillations, event-related oscillations, and coherences both in spontaneous EEG and event-related oscillations. The review clearly shows that, in cognitive impairment, fundamental changes are observed in all diseases under study. Accordingly, oscillations can most probably be used as biomarkers in clinical studies. The conclusions of this review include several remarks indicating the nature of brain oscillations, their application to cognitive processes, and the usefulness of recording brain oscillations in memory loss, attention deficit, and learning.

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