铋(III)盐促进和离子液体辅助高效、环保的一锅法合成1,5-苯二氮卓类衍生物。

ISRN Organic Chemistry Pub Date : 2011-05-14 eCollection Date: 2011-01-01 DOI:10.5402/2011/604348
Atul Chaskar, Latika Patil, Kiran Phatangare, Vikas Padalkar, Santosh Takale
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引用次数: 5

摘要

以铋(III)盐为催化剂,在温和条件下,邻苯二胺与酮类化合物缩合反应合成1,5-苯二氮卓类化合物。该方法简便、高效、环保,不含有毒催化剂,可获得优异的1,5 -苯二氮卓类药物收率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Bismuth (III) Salts Promoted and Ionic Liquid Assisted an Efficient and Environmentally Benign One-Pot Synthesis of 1,5-Benzodiazepine Derivatives.

Bismuth (III) Salts Promoted and Ionic Liquid Assisted an Efficient and Environmentally Benign One-Pot Synthesis of 1,5-Benzodiazepine Derivatives.

Bismuth (III) Salts Promoted and Ionic Liquid Assisted an Efficient and Environmentally Benign One-Pot Synthesis of 1,5-Benzodiazepine Derivatives.

1,5-Benzodiazepine derivatives were synthesized by the condensation reactions of o-phenylenediamine and ketones catalyzed by bismuth (III) salts under mild conditions. This method is easy, efficient, environment and eco-friendly, free of toxic catalysts, and gives good to excellent yields of 1, 5-benzodiazepines.

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