易碘催化吲哚与α,α′-双(芳基亚甲基)环戊酮的Michael加成:E-2-(3-吲哚苯基甲基)-5-苯基亚甲基环戊酮的高效合成

ISRN Organic Chemistry Pub Date : 2012-11-05 eCollection Date: 2012-01-01 DOI:10.5402/2012/674629
Rammohan Pal, Arpita Das Gupta, Asok K Mallik
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引用次数: 3

摘要

碘催化吲哚与α,α′-双(芳基亚甲基)环戊酮反应,得到相应的迈克尔加合物E-2-(3-吲哚苯基甲基)-5-苯基亚甲基环戊酮的一种非对映体,产率高。这些产物形成了一类新的吲哚衍生物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Facile Iodine-Catalyzed Michael Addition of Indoles to α,α'-Bis(arylmethylene)cyclopentanones: An Efficient Synthesis of E-2-(3-Indolylphenylmethyl)-5-phenylmethylenecyclopentanones.

Facile Iodine-Catalyzed Michael Addition of Indoles to α,α'-Bis(arylmethylene)cyclopentanones: An Efficient Synthesis of E-2-(3-Indolylphenylmethyl)-5-phenylmethylenecyclopentanones.

Facile Iodine-Catalyzed Michael Addition of Indoles to α,α'-Bis(arylmethylene)cyclopentanones: An Efficient Synthesis of E-2-(3-Indolylphenylmethyl)-5-phenylmethylenecyclopentanones.

Facile Iodine-Catalyzed Michael Addition of Indoles to α,α'-Bis(arylmethylene)cyclopentanones: An Efficient Synthesis of E-2-(3-Indolylphenylmethyl)-5-phenylmethylenecyclopentanones.

Iodine-catalyzed reaction of indoles with α,α'-bis(arylmethylene)cyclopentanones afforded one diastereomer of the corresponding Michael adducts, namely, E-2-(3-indolylphenylmethyl)-5-phenylmethylenecyclopentanones, in a good yield. The products form a new group of indole derivatives.

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