代谢组学在营养科学中的新兴作用。

Q Agricultural and Biological Sciences

Journal of Nutrigenetics and Nutrigenomics Pub Date : 2013-01-01 Epub Date: 2013-08-31 DOI:10.1159/000354403

Giuseppe Astarita, James Langridge

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引用次数: 76

摘要

在新技术工具的推动下，营养研究正在经历一场引人注目的变革。由于食物中存在的成分的复杂性以及它们如何与生物体的生化网络相互作用，营养学不能被认为是一门简化的学科。更全面的方法能够收集全面、高通量的大量数据，似乎能最好地增进我们对食物在健康和疾病中的作用的理解。在这种背景下，全球代谢物分析或“代谢组学”正在成为营养基因组学和营养遗传学科学家的一种有吸引力的研究工具。本文的目的是强调代谢组学在营养研究中的一些潜在应用。

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An emerging role for metabolomics in nutrition science.

Nutritional research is undergoing a remarkable transformation driven by new technological tools. Because of the complexity of the components present in food and how they may interact with the biochemical networks of living organisms, nutrition cannot be considered a reductionist discipline. More holistic approaches, which are capable of gathering comprehensive, high-throughput amounts of data, appear to best enhance our understanding of the role of food in health and disease. In this context, global metabolite analysis, or 'metabolomics', is becoming an appealing research tool for nutrigenomics and nutrigenetics scientists. The purpose of the present review is to highlight some potential applications of metabolomics in nutrition research.

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来源期刊

Journal of Nutrigenetics and Nutrigenomics GENETICS & HEREDITY-NUTRITION & DIETETICS

CiteScore

1.86

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The emerging field of nutrigenetics and nutrigenomics is rapidly gaining importance, and this new international journal has been established to meet the needs of the investigators for a high-quality platform for their research. Endorsed by the recently founded "International Society of Nutrigenetics/Nutrigenomics", the ‘Journal of Nutrigenetics and Nutrigenomics’ welcomes contributions not only investigating the role of genetic variation in response to diet and that of nutrients in the regulation of gene expression, but is also open for articles covering all aspects of gene-environment interactions in the determination of health and disease.