Ameeta E Singh, Bonita Lee, Jayne Fenton, Jutta Preiksaitis
{"title":"INSTI HIV-1/HIV-2抗体检测:综述","authors":"Ameeta E Singh, Bonita Lee, Jayne Fenton, Jutta Preiksaitis","doi":"10.1517/17530059.2013.774370","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Rapid HIV tests have been widely adopted globally as an important component of HIV prevention and control programs. The INSTI™ HIV-1/HIV-2 antibody test is a second-generation HIV antibody test, available in most countries for use from whole blood, serum, and plasma.</p><p><strong>Areas covered: </strong>Available data on kit characteristics and current performance data on the INSTI™ HIV-1/HIV-2 antibody test are presented together with six other rapid point-of-care tests (RPOCTs) for HIV antibody. Few published data are available providing direct comparisons of INSTI™ with other RPOCTs for HIV antibody and standard laboratory-based HIV-1/HIV-2 antibody assays. Existing data showed that INSTI™ has comparable performance to other RPOCTs but detected seroconversion later than standard laboratory-based assays.</p><p><strong>Expert opinion: </strong>The good performance of INSTI HIV-1/HIV-2 antibody test, its ease of use, the rapid availability of results (< 5 min), and the lack of specialized equipment required to use the kit make this kit a useful addition to the global market. The unique antigen and flow through technology contained in the kit make it a strong addition to HIV RPOCTs and to rapid/rapid algorithms used in many resource-limited settings.</p>","PeriodicalId":72996,"journal":{"name":"Expert opinion on medical diagnostics","volume":"7 3","pages":"299-308"},"PeriodicalIF":0.0000,"publicationDate":"2013-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1517/17530059.2013.774370","citationCount":"20","resultStr":"{\"title\":\"The INSTI HIV-1/HIV-2 antibody test: a review.\",\"authors\":\"Ameeta E Singh, Bonita Lee, Jayne Fenton, Jutta Preiksaitis\",\"doi\":\"10.1517/17530059.2013.774370\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Rapid HIV tests have been widely adopted globally as an important component of HIV prevention and control programs. The INSTI™ HIV-1/HIV-2 antibody test is a second-generation HIV antibody test, available in most countries for use from whole blood, serum, and plasma.</p><p><strong>Areas covered: </strong>Available data on kit characteristics and current performance data on the INSTI™ HIV-1/HIV-2 antibody test are presented together with six other rapid point-of-care tests (RPOCTs) for HIV antibody. Few published data are available providing direct comparisons of INSTI™ with other RPOCTs for HIV antibody and standard laboratory-based HIV-1/HIV-2 antibody assays. Existing data showed that INSTI™ has comparable performance to other RPOCTs but detected seroconversion later than standard laboratory-based assays.</p><p><strong>Expert opinion: </strong>The good performance of INSTI HIV-1/HIV-2 antibody test, its ease of use, the rapid availability of results (< 5 min), and the lack of specialized equipment required to use the kit make this kit a useful addition to the global market. The unique antigen and flow through technology contained in the kit make it a strong addition to HIV RPOCTs and to rapid/rapid algorithms used in many resource-limited settings.</p>\",\"PeriodicalId\":72996,\"journal\":{\"name\":\"Expert opinion on medical diagnostics\",\"volume\":\"7 3\",\"pages\":\"299-308\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2013-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1517/17530059.2013.774370\",\"citationCount\":\"20\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Expert opinion on medical diagnostics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1517/17530059.2013.774370\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2013/2/25 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Expert opinion on medical diagnostics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1517/17530059.2013.774370","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2013/2/25 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Introduction: Rapid HIV tests have been widely adopted globally as an important component of HIV prevention and control programs. The INSTI™ HIV-1/HIV-2 antibody test is a second-generation HIV antibody test, available in most countries for use from whole blood, serum, and plasma.
Areas covered: Available data on kit characteristics and current performance data on the INSTI™ HIV-1/HIV-2 antibody test are presented together with six other rapid point-of-care tests (RPOCTs) for HIV antibody. Few published data are available providing direct comparisons of INSTI™ with other RPOCTs for HIV antibody and standard laboratory-based HIV-1/HIV-2 antibody assays. Existing data showed that INSTI™ has comparable performance to other RPOCTs but detected seroconversion later than standard laboratory-based assays.
Expert opinion: The good performance of INSTI HIV-1/HIV-2 antibody test, its ease of use, the rapid availability of results (< 5 min), and the lack of specialized equipment required to use the kit make this kit a useful addition to the global market. The unique antigen and flow through technology contained in the kit make it a strong addition to HIV RPOCTs and to rapid/rapid algorithms used in many resource-limited settings.
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