[用于检测感染因子或其产物的酶免疫测定:一些设计和应用的介绍]。

Q4 Medicine
Revista Cubana de Medicina Tropical Pub Date : 2010-09-01
Anselmo J Otero González
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引用次数: 0

摘要

本文评估了免疫酶分析在过去40年中对基于免疫化学的分析领域的影响,以及对感染因子或与其存在和/或致病活性相关的产物的检测的影响。它还讨论了这些免疫测定的一些设计和格式,从电化学检测方法,测定蛋白水解微生物活性及其抑制剂作为可能的治疗靶点的测定,更敏感的直接三重抗体系统,替代酶活性检测器,最小测定的病毒血清学测定到基于选定肽组合评估疫苗候选有效性的竞争性测定。最后,它提供了在新兴的检测分析技术的光这种类型的免疫测定的近期的快速概述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Enzymatic immunoassays for the detection of infectious agents or their products: presentation of some designs and applications].

This paper assessed the impact of the immunoenzymatic assays on the field of the immunochemistry-based analytics for the last 40 years, and on the detection of infectious agents or the products related to their presence and/or pathogenic activity. It also addressed some designs and formats of these immunoassays from electrochemical methods of detection, assays to determine proteolytic microbial activity and their inhibitors as possible therapeutical targets, more sensitive direct triple antibody systems, alternative enzymatic activity detectors, assays for viral serology of minimal determinations to competitive assays for evaluation of vaccinal candidate effectiveness based on selected peptide combinations. Finally, it provided a rapid overview of the near future of this type of immunoassays in the light of the emerging detection analytical technologies.

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来源期刊
Revista Cubana de Medicina Tropical
Revista Cubana de Medicina Tropical Medicine-Infectious Diseases
CiteScore
0.30
自引率
0.00%
发文量
0
期刊介绍: La Revista Cubana de Medicina Tropical tiene la misión de publicar artículos científicos especializados en medicina tropical, microbiología, parasitología, epidemiología y otras especialidades afines. Se distribuye directamente por el editor a los suscriptores en formato impreso (ISSN 0375-0760). Está dirigida a profesionales y técnicos en el campo de la medicina tropical, microbiología, parasitología y epidemiología. Recibe contribuciones en idioma español, inglés y portugués sin distinción en el país de procedencia.
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