从火鸡中分离的低致病性禽流感病毒(H6N1)的特性分析。

Influenza research and treatment Pub Date : 2011-01-01 Epub Date: 2010-12-30 DOI:10.1155/2011/285218
I Shkoda, E Lapin, E Rosenbluth, S Perk, Z Geva, A Inbar, I Davidson
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引用次数: 1

摘要

从表现出典型的与禽流感病毒感染相关病理的火鸡家禽中分离出甲型/火鸡/以色列/09亚型H6N1禽流感病毒。采用AIV亚型特异性引物进行RT-PCR鉴定,采用AIV亚型特异性抗血清进行血凝抑制试验。该病毒静脉内致病性指数为0,在血凝素基因PQIETR*GLF的裂解位点具有与低致病性禽流感病毒相关的核苷酸序列。与之前从家鸭和野鸭中分离出的H6N2不同,A/turkey/Israel/09 (H6N1)是从火鸡中分离出来的。A/土耳其/以色列/09 (H6N1)病毒的基因序列与先前的以色列H6分离株存在差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Characterization of a Low Pathogenic Avian Influenza Virus (H6N1) Isolated from Turkeys.

Characterization of a Low Pathogenic Avian Influenza Virus (H6N1) Isolated from Turkeys.

Characterization of a Low Pathogenic Avian Influenza Virus (H6N1) Isolated from Turkeys.

Characterization of a Low Pathogenic Avian Influenza Virus (H6N1) Isolated from Turkeys.

An avian influenza virus (AIV), A/turkey/Israel/09 subtype H6N1, was isolated from turkey poults exhibiting typical pathology associated with AIV infection. The virus was characterized by RT-PCR using AIV subtype-specific primers and by the haemagglutination inhibition test using AIV subtype-specific antisera. The virus has an intravenous pathogenicity index of 0 and possessed a nucleotide sequence at the cleavage site of the hemagglutinin gene, PQIETR*GLF, associated with avian influenza viruses of low pathogenicity. Unlike the two previous H6N2 isolates originating from domestic ducks and mallard, the A/turkey/Israel/09 (H6N1) was isolated from turkeys. The gene sequences of the A/turkey/Israel/09 (H6N1) virus show divergence from the former Israeli H6 isolates.

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