颞叶癫痫中的抑郁症:发病率、临床特征和管理注意事项综述。

Epilepsy research and treatment Pub Date : 2012-01-01 Epub Date: 2011-12-01 DOI:10.1155/2012/809843
C S Garcia
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引用次数: 0

摘要

颞叶癫痫患者常伴有抑郁,这已被证实是一种常见病,人们也提出了导致这种严重并发症的各种可能机制。然而,临床医生在识别和处理颞叶癫痫患者的抑郁方面仍缺乏指导。这部分是由于早期的研究缺乏一致的发现,部分原因可能是由于方法、取样以及颞叶癫痫和抑郁症的诊断存在差异。然而,近年来,人们已做出巨大努力来解决这些问题,并为这一人群的抑郁症诊断和管理提供了一个框架。以下是文献综述,特别强调抑郁症状的临床现象学、抑郁症与颞叶癫痫之间的双向风险描述,以及与抗癫痫药物潜在药物相互作用背景下的治疗策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Depression in temporal lobe epilepsy: a review of prevalence, clinical features, and management considerations.

Depression in temporal lobe epilepsy has been established as a frequent occurrence, and various possible mechanisms for this significant comorbidity have been posited. However, there is still little to guide a clinician in the recognition and management of depression in patients with temporal lobe epilepsy. This is in part due to the lack of consistent findings in earlier studies, which was likely partly due to variabilities in methodology, sampling, and diagnosis of both temporal lobe epilepsy and depression. However, in recent years, significant effort has been made to address these issues and provide a framework for diagnosis and management of depression in this population. The following is a review of the literature, with special emphasis on clinical phenomenology of depressive symptoms, described bidirectional risk between depression and temporal lobe epilepsy, and treatment strategies in the context of potential drug interactions with antiepileptic drugs.

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