积极监控低风险前列腺癌。

F1000 medicine reports Pub Date : 2012-01-01 Epub Date: 2012-08-01 DOI:10.3410/M4-16
Laurence Klotz
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引用次数: 0

摘要

对局部前列腺癌的积极监测需要进行初步的预期管理,而不是立即治疗,"治愈性 "治疗将推迟到有证据表明患者的疾病进展风险增加时进行。这是对有明确记载的过度诊断和过度治疗低危前列腺癌风险的回应,在大多数情况下,低危前列腺癌对患者几乎不构成威胁。它以前列腺癌漫长的自然病史为基础,试图在过度治疗的风险和副作用与疾病进展和失去治愈机会的可能性之间取得平衡。低危前列腺癌更准确地说是高危前列腺癌的多种风险因素之一。与不典型小尖锐湿疣增生(ASAP)一样,除非有明确证据表明病情更具侵袭性,否则可对其进行密切随访,但不采取根治性干预措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Active surveillance for low-risk prostate cancer.

Active surveillance for low-risk prostate cancer.

Active surveillance for localized prostate cancer entails initial expectant management rather than immediate therapy, with "curative-intent" treatment deferred until there is evidence that the patient is at increased risk for disease progression. This is a response to the clearly documented risks of over diagnosis and overtreatment of low-risk prostate cancer, which in most cases poses little or no threat to the patient. It is based upon the prolonged natural history of prostate cancer and is an attempt to balance the risks and side effects of overtreatment against the possibility of disease progression and a lost opportunity for cure. Low-risk prostate cancer is more accurately viewed as one of multiple risk factors for the presence of higher grade prostate cancer. Like atypical small acinar proliferation, (ASAP), it may be managed with close follow up but without radical intervention, unless there is clear evidence of more aggressive disease.

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