{"title":"具有适体控制的靶向递送启闭功能的DNA纳米胶囊。","authors":"Thomas Bentin","doi":"10.4161/adna.19843","DOIUrl":null,"url":null,"abstract":"<p><p>A DNA capsule fitted with aptamer controlled target sensing has been \"woven\" using a 7308-base single-stranded DNA \"thread\" and 196 staple oligonucleotides. The capsule enables logic-gated molecular cargo delivery to targeted cell surfaces.</p>","PeriodicalId":8444,"journal":{"name":"Artificial DNA: PNA & XNA","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4161/adna.19843","citationCount":"5","resultStr":"{\"title\":\"A DNA nanocapsule with aptamer-controlled open-closure function for targeted delivery.\",\"authors\":\"Thomas Bentin\",\"doi\":\"10.4161/adna.19843\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A DNA capsule fitted with aptamer controlled target sensing has been \\\"woven\\\" using a 7308-base single-stranded DNA \\\"thread\\\" and 196 staple oligonucleotides. The capsule enables logic-gated molecular cargo delivery to targeted cell surfaces.</p>\",\"PeriodicalId\":8444,\"journal\":{\"name\":\"Artificial DNA: PNA & XNA\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.4161/adna.19843\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Artificial DNA: PNA & XNA\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4161/adna.19843\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Artificial DNA: PNA & XNA","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4161/adna.19843","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A DNA nanocapsule with aptamer-controlled open-closure function for targeted delivery.
A DNA capsule fitted with aptamer controlled target sensing has been "woven" using a 7308-base single-stranded DNA "thread" and 196 staple oligonucleotides. The capsule enables logic-gated molecular cargo delivery to targeted cell surfaces.
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