一项评估水法在美国社区辅助结肠镜插入可行性的试点研究。

Donald J Portocarrero, Kendrick Che, Snorri Olafsson, Michael H Walter, Christian S Jackson, Felix W Leung, Ariel Malamud
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引用次数: 11

摘要

背景:水法减少患者不适和镇静需求。在美国非退伍军人社区的适用性尚未有报道。目的:我们的目标是进行一项试点研究,以确定在两个社区站点使用水方法的可行性。我们验证了这样的假设:与空气充气相比,用水法检查的患者需要更少的镇静,而不会对结果产生不利影响。方法:实施两个绩效改进项目。在结肠镜检查后同意回答问卷的连续患者被纳入研究。项目1:设计为单盲(仅限患者);准随机-奇数天(水),偶数天(空气)。结肠镜检查由一名主治医生进行。项目2:一名受监督的受训人员执行报告的程序。两组患者的人口统计数据(年龄、性别和体重指数)、结肠镜检查时所需的镇静量和手术相关变量均被记录。患者完成一份调查问卷,询问结肠镜检查期间的不适情况以及术后24小时内是否愿意重复检查。结果:项目一:水组芬太尼、咪达唑仑剂量明显降低,腺瘤检出率(ADR)较高。项目二:指导学员盲肠插管率100%。结论:这是美国第一份试点报告,记录了水法作为辅助男性和女性社区患者结肠镜插入的主要方式的可行性。在头对头比较中,镇静需求的显著减少被证实为假设。未发现对结果的不利影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A pilot study to assess feasibility of the water method to aid colonoscope insertion in community settings in the United States.

BACKGROUND: The water method decreases patient discomfort and sedation requirement. Applicability in non-veteran community settings in the United States (U.S.) has not been reported. AIMS: Our aim is to perform a pilot study to establish feasibility of use the water method at 2 community sites. We tested the hypothesis that compared with air insufflation patients examined with the water method would require less sedation without adverse impact on outcomes. METHODS: Two performance improvement projects were carried out. Consecutive patients who consented to respond to a questionnaire after colonoscopy were enrolled. Project 1: The design was single-blinded (patient only); quasi-randomized - odd days (water), even days (air). Colonoscopy was performed by a staff attending. Project 2: A supervised trainee performed the reported procedures. In both, patient demographics (age, gender and body mass index), amount of sedation required during colonoscopy and procedure-related variables were recorded. The patients completed a questionnaire that enquired about discomfort during colonoscopy and willingness to repeat the procedure within 24 hours after the procedure. RESULTS: Project 1: Significantly lower doses of fentanyl and midazolam were used and a higher adenoma detection rate (ADR) was demonstrated in the water group. Project 2: 100% cecal intubation rate was achieved by the supervised trainee. CONCLUSION: This is the first pilot report in the U.S. documenting feasibility of the water method as the principal modality to aid colonoscope insertion in both male and female community patients. In a head-to-head comparison, significant reduction of sedation requirement is confirmed as hypothesized. No adverse impact on outcomes was noted.

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