疼痛作为肋骨固定的指征:一项双机构的试点研究。

Marc de Moya, Thanos Bramos, Suresh Agarwal, Karim Fikry, Sumbal Janjua, David R King, Hasan B Alam, George C Velmahos, Peter Burke, William Tobler
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引用次数: 72

摘要

背景:在创伤患者中,肋骨骨折的切开复位和内固定仍然存在争议。我们假设,与对照组相比,接受肋骨骨折切开复位和内固定的患者会经历更少的疼痛,因此需要更少的阿片类药物。此外,我们假设改善疼痛控制将导致更少的肺部并发症和缩短住院时间。方法:这是一项回顾性的双机构匹配病例对照研究。年龄、损伤严重程度评分、胸部缩窄性损伤严重程度评分、头部缩窄性损伤严重程度评分、肺挫伤评分、肋骨骨折数按1:2匹配。每日镇痛药物总剂量转换为等镇痛静脉注射吗啡剂量,主要结局为住院麻醉给药。结果:2005年7月至2009年6月间,16例患者在伤后5±3天内平均使用3(1-5)块金属钢板固定肋骨。吗啡需用量由术前110 mg±98 mg降至术后63±57 mg (p = 0.01)。在吗啡平均剂量(79±63 vs 76±55 mg, p = 0.65)、住院时间(18±12 vs 16±11天,p = 0.67)、重症监护病房住院时间(9±8 vs 7±10天,p = 0.75)、通气天数(7±8 vs 6±10天,p = 0.44)和肺炎发生率(31% vs 38%, p = 0.76)方面,病例与对照组无显著差异。结论:多发肋骨骨折患者肋骨固定术后镇痛需求明显减少。然而,在这项初步研究中,这些患者与匹配的对照组相比,没有观察到结果的差异。需要进一步研究来调查这些初步发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pain as an indication for rib fixation: a bi-institutional pilot study.

Background: In trauma patients, open reduction and internal fixation of rib fractures remain controversial. We hypothesized that patients who have open reduction and internal fixation of rib fractures would experience less pain compared with controls and thus require fewer opiates. Further, we hypothesized that improved pain control would result in fewer pulmonary complications and decreased length of stay.

Methods: This is a retrospective bi-institutional matched case-control study. Cases were matched 1:2 by age, injury severity Score, chest abbreviated injury severity score, head abbreviated injury severity score, pulmonary contusion score, and number of fractured ribs. The daily total doses of analgesic drugs were converted to equianalgesic intravenous morphine doses, and the primary outcome was inpatient narcotic administration.

Results: Sixteen patients between July 2005 and June 2009 underwent rib fixation in 5 ± 3 days after injury using an average of 3 (1-5) metallic plates. Morphine requirements decreased from 110 mg ± 98 mg preoperatively to 63 ± 57 mg postoperatively (p = 0.01). There were no significant differences between cases and controls in the mean morphine dose (79 ± 63 vs. 76 ± 55 mg, p = 0.65), hospital stay (18 ± 12 vs. 16 ± 11 days, p = 0.67), intensive care unit stay (9 ± 8 vs. 7 ± 10 days, p = 0.75), ventilation days (7 ± 8 vs. 6 ± 10, p = 0.44), and pneumonia rates (31% vs. 38%, p = 0.76).

Conclusion: The need for analgesia was significantly reduced after rib fixation in patients with multiple rib fractures. However, no difference in outcomes was observed when these patients were compared with matched controls in this pilot study. Further study is required to investigate these preliminary findings.

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来源期刊
Journal of Trauma-Injury Infection and Critical Care
Journal of Trauma-Injury Infection and Critical Care CRITICAL CARE MEDICINE-EMERGENCY MEDICINE
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