验证西方创伤协会算法管理前腹部刺伤患者:西方创伤协会多中心试验。

Walter L Biffl, Krista L Kaups, Tam N Pham, Susan E Rowell, Gregory J Jurkovich, Clay Cothren Burlew, J Elterman, Ernest E Moore
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引用次数: 69

摘要

未标记:稳定的前腹部刺伤(AASWs)患者的最佳管理仍然是一个有争议的问题。最近西方创伤协会(WTA)的一项多中心试验发现,通过局部伤口探查(LWE)排除腹膜穿透可以使41%的AASWs患者立即出院。计算机断层扫描(CT)或诊断性腹腔灌洗(DPL)没有提高D/C率;然而,这些测试分别导致24%和31%的病例进行非治疗性(NONTHER)剖腹手术。我们提出了一种算法,包括LWE,然后是D/C或入院进行一系列临床评估,而不需要进一步的成像或侵入性检查。本研究的目的是评估该算法在为重大损伤提供及时干预方面的安全性和有效性。方法:一项多中心、机构审查委员会批准的研究纳入了AASWs患者。管理以WTA AASW算法为指导。前瞻性地记录患者的表现、评估和临床过程。结果:共纳入222例患者(94%为男性,年龄34.7±0.3岁)。62例(28%)立即发生LAP,其中87%为治疗性(THER)。3例(1%)死亡,平均住院时间(LOS)为6.9天。160例患者稳定且无症状,其中81例(51%)完全按照方案进行管理。20例(25%)患者在(-)LWE后被急诊科D/C, 11例(14%)患者在临床情况发生变化后被送往手术室(OR)进行LAP。方案组中2例(2%)患者接受了NONTHER LAP治疗,没有患者出现与治疗延迟相关的发病率或死亡率。79例(49%)患者偏离方案。CT扫描47次,dpl 11次,腹腔镜探查9次。除腹腔镜手术外,38例(48%)患者是根据检查结果而不是患者临床状况的变化被送往手术室的;其中17例(45%)患者进行了NONTHER LAP。18例(23%)患者从急诊科被D/C。即时或延迟LAP患者的LOS无差异。NONTHER LAP术后平均LOS为3.6天±0.8天。结论:WTA提出的算法具有成本效益。连续的临床评估可以在不增加CT、DPL或腹腔镜检查费用的情况下进行。需要LAP的患者通常在病程早期就表现出来,并且似乎没有任何与延迟到手术室相关的发病率。这些数据验证了该方法,需要在更多的患者中得到证实,以更有说服力地评估该算法与其他方法相比的安全性和成本效益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Validating the Western Trauma Association algorithm for managing patients with anterior abdominal stab wounds: a Western Trauma Association multicenter trial.

Unlabelled: The optimal management of stable patients with anterior abdominal stab wounds (AASWs) remains a matter of debate. A recent Western Trauma Association (WTA) multicenter trial found that exclusion of peritoneal penetration by local wound exploration (LWE) allowed immediate discharge (D/C) of 41% of patients with AASWs. Performance of computed tomography (CT) scanning or diagnostic peritoneal lavage (DPL) did not improve the D/C rate; however, these tests led to nontherapeutic (NONTHER) laparotomy (LAP) in 24% and 31% of cases, respectively. An algorithm was proposed that included LWE, followed by either D/C or admission for serial clinical assessments, without further imaging or invasive testing. The purpose of this study was to evaluate the safety and efficacy of the algorithm in providing timely interventions for significant injuries.

Methods: A multicenter, institutional review board-approved study enrolled patients with AASWs. Management was guided by the WTA AASW algorithm. Data on the presentation, evaluation, and clinical course were recorded prospectively.

Results: Two hundred twenty-two patients (94% men, age, 34.7 years ± 0.3 years) were enrolled. Sixty-two (28%) had immediate LAP, of which 87% were therapeutic (THER). Three (1%) died and the mean length of stay (LOS) was 6.9 days. One hundred sixty patients were stable and asymptomatic, and 81 of them (51%) were managed entirely per protocol. Twenty (25%) were D/C'ed from the emergency department after (-) LWE, and 11 (14%) were taken to the operating room (OR) for LAP when their clinical condition changed. Two (2%) of the protocol group underwent NONTHER LAP, and no patient experienced morbidity or mortality related to delay in treatment. Seventy-nine (49%) patients had deviations from protocol. There were 47 CT scans, 11 DPLs, and 9 laparoscopic explorations performed. In addition to the laparoscopic procedures, 38 (48%) patients were taken to the OR based on test results rather than a change in the patient's clinical condition; 17 (45%) of these patients had a NONTHER LAP. Eighteen (23%) patients were D/C'ed from the emergency department. The LOS was no different among patients who had immediate or delayed LAP. Mean LOS after NONTHER LAP was 3.6 days ± 0.8 days.

Conclusions: The WTA proposed algorithm is designed for cost-effectiveness. Serial clinical assessments can be performed without the added expense of CT, DPL, or laparoscopy. Patients requiring LAP generally manifest early in their course, and there does not appear to be any morbidity related to a delay to OR. These data validate this approach and should be confirmed in a larger number of patients to more convincingly evaluate the algorithm's safety and cost-effectiveness compared with other approaches.

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Journal of Trauma-Injury Infection and Critical Care
Journal of Trauma-Injury Infection and Critical Care CRITICAL CARE MEDICINE-EMERGENCY MEDICINE
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