卵巢癌在普通人群中的筛查和早期发现。

Reviews in obstetrics & gynecology Pub Date : 2011-01-01
Jose A Rauh-Hain, Thomas C Krivak, Marcela G Del Carmen, Alexander B Olawaiye
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引用次数: 0

摘要

在世界范围内,卵巢癌的年发病率估计为204,000例,死亡人数为125,000例。在发达国家,卵巢癌仍然是所有妇科恶性肿瘤中最致命的。死亡率高的原因之一是,超过70%的卵巢癌妇女被诊断为晚期疾病。发病阶段与生存率密切相关;因此,卵巢癌的早期发现是降低死亡率和长期控制疾病的最佳希望。有初步证据表明,筛查可以提高生存率,但筛查对卵巢癌死亡率的影响尚不清楚。蛋白质组学方法已经产生了令人鼓舞的初步发现,但这些发现还不够成熟,不能用于临床应用。目前,无法根据现有数据提出明确的建议。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ovarian cancer screening and early detection in the general population.

Worldwide, the estimated annual incidence of ovarian cancer is 204,000, with 125,000 deaths. In developed countries, ovarian cancer remains the most lethal of all gynecologic malignancies. One of the reasons for the high fatality rate is that more than 70% of women with ovarian cancer are diagnosed with advanced disease. There is a close correlation between stage at presentation and survival; therefore, early detection of ovarian cancer represents the best hope for mortality reduction and long-term disease control. There is preliminary evidence that screening can improve survival, but the impact of screening on mortality from ovarian cancer is still unclear. The proteomic approach has yielded encouraging preliminary findings, but these findings are not mature enough for clinical use. At this time, clear recommendations cannot be made on the basis of the available data.

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